5-Methoxysalicylic Acid
5-Methoxysalicylic Acid structure
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Common Name | 5-Methoxysalicylic Acid | ||
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| CAS Number | 2612-02-4 | Molecular Weight | 168.147 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 347.0±27.0 °C at 760 mmHg | |
| Molecular Formula | C8H8O4 | Melting Point | 141-143 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 146.5±17.2 °C | |
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Profiling Aglycon-Recognizing Sites of UDP-glucose:glycoprotein Glucosyltransferase by Means of Squarate-Mediated Labeling.
Biochemistry 54 , 4909-17, (2015) Because of its ability to selectively glucosylate misfolded glycoproteins, UDP-glucose:glycoprotein glucosyltransferase (UGGT) functions as a folding sensor in the glycoprotein quality control system in the endoplasmic reticulum (ER). The unique property of U... |
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Catalytic activation of pre-substrates via dynamic fragment assembly on protein templates.
Nat. Commun. 5 , 5170, (2014) Sensitive detection of small molecule fragments binding to defined sites of biomacromolecules is still a considerable challenge. Here we demonstrate that protein-binding fragments are able to induce enzymatic reactions on the protein surface via dynamic fragm... |
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Chemical characterization of milk oligosaccharides of the eastern quoll (Dasyurus viverrinus).
Glycoconj. J. 32 , 361-70, (2015) Structural characterizations of marsupial milk oligosaccharides have been performed in four species to date: the tammar wallaby (Macropus eugenii), the red kangaroo (Macropus rufus), the koala (Phascolarctos cinereus) and the common brushtail possum (Trichosu... |
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Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome.
Anal. Chem. 81(10) , 3919-32, (2009) We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass s... |
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Macroporous cryogel based spin column with immobilized concanavalin A for isolation of glycoproteins.
Electrophoresis 36 , 1344-8, (2015) In this work we have developed a hydrophilic poly(hydroxyethyl methacrylate-co-poly(ethylene glycol) diacrylate) cryogel placed in the centrifugal filter device. The composition of the polymerization mixture as well as the polymerization conditions were optim... |
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A thiophene-containing compound as a matrix for matrix-assisted laser desorption/ ionization mass spectrometry and the electrical conductivity of matrix crystals.
Eur. J. Mass Spectrom. (Chichester, Eng.) 19(1) , 29-37, (2013) The electrical conductivity of the matrix crystal might be a new factor to enhance matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) sensitivity. In MALDI-MS, several compounds are used as a standard matrix. Utilization of such compound... |
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(E)-Propyl α-Cyano-4-Hydroxyl Cinnamylate: A High Sensitive and Salt Tolerant Matrix for Intact Protein Profiling by MALDI Mass Spectrometry.
J. Am. Soc. Mass Spectrom. 27 , 709-18, (2016) Low-abundance samples and salt interference are always of great challenges for the practical protein profiling by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Herein, a series of carboxyl-esterified derivatives of α-cyano-4-hydrox... |
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Enhanced rectal bioavailability of polypeptides using sodium 5-methoxysalicylate as an absorption promoter.
J. Pharm. Sci. 71(5) , 593-4, (1982) The absorption-promoting effect of sodium 5-methoxysalicylate was studied in the rat with respect to rectal delivery of pentagastrin and gastrin. Rectal bioavailability was quantitated by direct comparison of pharmacological effect with intravenous dose respo... |
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Effects of sodium 5-methoxysalicylate on macromolecule absorption and mucosal morphology in a vascularly perfused rat gut preparation in vivo.
J. Pharm. Sci. 76(12) , 857-61, (1987) The effect of sodium 5-methoxysalicylate on absorption was assessed by measurement of the appearance of test compounds in the portal blood output of a perfused rat gut model. The test compounds were a hexapeptide analogue of somatostatin, insulin, and horsera... |
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DFT, FT-Raman and FT-IR investigations of 5-methoxysalicylic acid.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 82(1) , 504-12, (2011) FT-IR and FT-Raman spectra of 5-methoxysalicylic acid (5MeOSA) have been experimentally reported in the region of 4000-10 cm(-1) and 4000-50 cm(-1), respectively. The optimized geometric parameters, conformational equilibria, normal mode frequencies and corre... |