pyrrolidone hydrotribromide
pyrrolidone hydrotribromide structure
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Common Name | pyrrolidone hydrotribromide | ||
|---|---|---|---|---|
| CAS Number | 22580-55-8 | Molecular Weight | 324.81600 | |
| Density | 1.047g/cm3 | Boiling Point | 245ºC at 760mmHg | |
| Molecular Formula | C4H7Br3NO | Melting Point | 87-91ºC | |
| MSDS | Chinese USA | Flash Point | 135.5ºC | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Influence of Parathyroid Hormone-Loaded PLGA Nanoparticles in Porous Scaffolds for Bone Regeneration.
Int. J. Mol. Sci. 16 , 20492-510, (2015) Biodegradable poly(lactide-co-glycolide) (PLGA) nanoparticles, containing human parathyroid hormone (PTH (1-34)), prepared by a modified double emulsion-solvent diffusion-evaporation method, were incorporated in porous freeze-dried chitosan-gelatin (CH-G) sca... |
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Ornithine Transcarbamylase ArgK Plays a Dual role for the Self-defense of Phaseolotoxin Producing Pseudomonas syringae pv. phaseolicola.
Sci. Rep. 5 , 12892, (2015) Pseudomonas syringae is a phytopathogenic bacterium widely spread on terrestrial plants. Sulfodiaminophosphinyl tripeptide Phaseolotoxins (PHTs), produced by P. syringae pv. phaseolicola and P. syringae pv. actinidiae, represent a kind of antimetabolic phytot... |
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Reversal of P-glycoprotein overexpression by Ginkgo biloba extract in the brains of pentylenetetrazole-kindled and phenytoin-treated mice.
Kaohsiung J. Med. Sci. 31 , 398-404, (2015) The purpose of this study was to investigate the combined effects of Ginkgo biloba extract and phenytoin (PHT) sodium as a dose regimen simulating the clinical treatment of patients with epilepsy, on P-glycoprotein (P-GP) overexpression in a pentylenetetrazol... |
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Elevated Expression of the Delta-Subunit of Epithelial Sodium Channel in Temporal Lobe Epilepsy Patients and Rat Model.
J. Mol. Neurosci. 57 , 510-8, (2015) Epilepsy is one of the most common, chronic, neurological diseases. The pathology of epilepsy is based on abnormal synchronization of neuronal discharges. Epithelial sodium channels, which are constitutively active, non-voltage-gated, highly selective sodium ... |
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Anticonvulsive and neuroprotective effects of synergetic combination of phenytoin and gastrodin on the convulsion induced by penicillin in mice.
Fundam. Clin. Pharmacol. 29 , 371-81, (2015) Phenytoin (PHT) is a commonly prescribed first-line antiepileptic drug. However, long-term administration of PHT can cause memory loss and balance disturbance. Gastrodin (GD) is the major bioactive component in Tianma and has sedative, anticonvulsive, memory ... |
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Involvement of p38 MAPK in the Drug Resistance of Refractory Epilepsy Through the Regulation Multidrug Resistance-Associated Protein 1.
Neurochem. Res. 40 , 1546-53, (2015) Increased expression of multidrug-resistance associated protein 1 in brain tissue has been reported which lead to multidrug resistance of refractory epilepsy. However, the mechanism of up-regulated expression is still unclear. In our previous study, we have f... |
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Absence-like seizures and their pharmacological profile in tottering-6j mice.
Biochem. Biophys. Res. Commun. 463 , 148-53, (2015) We previously showed that recessive ataxic tottering-6j mice carried a base substitution (C-to-A) in the consensus splice acceptor sequence linked to exon 5 of the α1 subunit of the Cav2.1 channel gene (Cacna1a), resulting in the skipping of exon 5 and deleti... |
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Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells.
Int. J. Oncol. 48 , 73-83, (2016) Voltage-gated Na+ channels (VGSCs) are membrane proteins which are normally expressed in excitable cells but have also been detected in cancer cells, where they are thought to be involved in malignancy progression. In this study we examined the ion current an... |
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Pyrrolidone hydrotribromide: a brominating agent with selectivity for ketones.
Can. J. Chem. 47(4) , 706-709, (1969)
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The microRNA miR-124 suppresses seizure activity and regulates CREB1 activity.
Expert Rev. Mol. Med. 18 , e4, (2016) miR-124, a brain-specific microRNA, was originally considered as a key regulator in neuronal differentiation and the development of the nervous system. Here we showed that miR-124 expression was suppressed in patients with epilepsy and rats after drug induced... |