Akt Inhibitor IV
Akt Inhibitor IV structure
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Common Name | Akt Inhibitor IV | ||
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| CAS Number | 681281-88-9 | Molecular Weight | 614.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H27IN4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia.
J. Thorac. Cardiovasc. Surg. 286 , 9393-404, (2011) Hypoxia promotes neural stem cell proliferation, the mechanism of which is poorly understood. Here, we have identified the nuclear orphan receptor TLX as a mediator for proliferation and pluripotency of neural progenitors upon hypoxia. We found an enhanced ea... |
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Akt signaling pathway: a target for radiosensitizing human malignant glioma.
Neuro. Oncol. 12 , 434-43, (2010) Radiation therapy plays a central role in the treatment of glioblastoma, but it is not curative due to the high tumor radioresistance. Phosphatidyl-inositol 3-kinase/protein kinase B (Akt) and Janus kinase (JAK)/signal transducer and activator of transcriptio... |
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