681281-88-9
681281-88-9 structure
- Name: Akt Inhibitor IV
- Chemical Name: 6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide
- CAS Number: 681281-88-9
- Molecular Formula: C31H27IN4S
- Molecular Weight: 614.54
- Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
- Create Date: 2016-08-02 22:40:08
- Modify Date: 2025-09-01 15:46:44
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Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity[1].
| Name | 6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide |
|---|---|
| Synonyms |
5-(2-benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1h-benzimidazolium iodide
akt inhibitor iv |
| Description | Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C31H27IN4S |
|---|---|
| Molecular Weight | 614.54 |
| Exact Mass | 614.10000 |
| PSA | 53.18000 |
| LogP | 8.31990 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| RIDADR | NONH for all modes of transport |
|
~88%
681281-88-9 |
| Literature: Sun, Qi; Wu, Runzhi; Cai, Sutang; Lin, Yuan; Sellers, Llewlyn; Sakamoto, Kaori; He, Biao; Peterson, Blake R. Journal of Medicinal Chemistry, 2011 , vol. 54, # 5 p. 1126 - 1139 |
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681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
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681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
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681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
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~%
681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
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~%
681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
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~%
681281-88-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1126 - 1139 |
| Precursor 6 | |
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| DownStream 0 | |