(-)-Citreoviridin

(-)-Citreoviridin Structure
(-)-Citreoviridin structure
Common Name (-)-Citreoviridin
CAS Number 25425-12-1 Molecular Weight 402.481
Density 1.2±0.1 g/cm3 Boiling Point 585.1±50.0 °C at 760 mmHg
Molecular Formula C23H30O6 Melting Point 107-111℃
MSDS USA Flash Point 197.7±23.6 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Co-occurrence of aflatoxins B₁, B₂, G₁ and G₂, ochratoxin A, zearalenone, deoxynivalenol, and citreoviridin in rice in Brazil.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(4) , 694-703, (2012)

A total of 230 samples of processed rice and its sub-products or derived products were analysed to establish the co-occurrence of several mycotoxins. Samples were analysed in the period 2007-2009 due to the outbreak of beriberi associated with the consumption...

Production of citreoviridin by Penicillium citreonigrum strains associated with rice consumption and beriberi cases in the Maranhão State, Brazil.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 27(2) , 241-8, (2010)

The aim of this study was to determine the levels of Penicillium citreonigrum and citreoviridin present in rice samples from Maranhão State, Brazil, where an outbreak of beriberi was reported and 32 deaths occurred (7% of the notified cases died in 2006). The...

Effect of citreoviridin and isocitreoviridin on beef heart mitochondrial ATPase.

Arch. Biochem. Biophys. 270(2) , 714-21, (1989)

Citreoviridin is a toxic metabolite from fungus that has been shown to be an inhibitor of mitochondrial F1-ATPases. Studies of citreoviridin, however, have been compromised by the light-dependent isomerization that it undergoes. The isomerization is a potenti...

Effect of citreoviridin, a mycotoxin from Penicillium citreoviride, on kinetic constants of acetylcholinesterase and ATPase in synaptosomes and microsomes from rat brain.

Toxicon 19(4) , 555-62, (1981)

In vitro inhibitory activity of citreoviridin against HIV-1 and an HIV-associated opportunist: Candida albicans.

J. Chemother. 8(5) , 351-7, (1996)

Citreoviridin, a mycotoxin produced by some molds of the genera Penicillium and Aspergillus, inhibits the growth of bacteria of the Bacillus genus. Since significant information was not available on the effects of citreoviridin on eukaryotic cells and viruses...

Influence of efrapeptin, aurovertin and citreoviridin on the mitochondrial adenosine triphosphatase from Trypanosoma cruzi.

Mol. Biochem. Parasitol. 3(3) , 143-55, (1981)

Steady-state velocity studies using a substrate regenerating system showed that efrapeptin, citreoviridin and aurovertin inhibit both membrane-bound and soluble mitochondrial ATPase (coupling factor F1) from Trypanosoma cruzi. Maximal inhibitions of ATP hydro...

Chronic exposure to cereal mycotoxin likely citreoviridin may be a trigger for Keshan disease mainly through oxidative stress mechanism

Med. Hypotheses 74(5) , 841-2, (2010)

The origin of Keshan disease (KD), an endemic cardiomyopathy particularly affected children and young women in China, has been a controversial and difficult problem in academics over the past decades. We hypothesize that mycotoxins likely citreoviridin may in...

[Effects of citreoviridin on the expression of MCP-1 and ILs induced by TNF-alpha in vein endothelial cells].

Wei Sheng Yan Jiu 41(2) , 195-8, 203, (2012)

To investigate the effects of citreoviridin (CIT) on the expression of MCP-1, IL-1beta, IL-6 and IL-8 induced by TNF-alpha in human umbilical vein endothelial cells (HUVECs).HUVECs isolated from the umbilical cord of neonates within 1 hour after birth (inform...

[Injury in myocardial cells induced by citreoviridin].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 24(3) , 177-8, (2006)

The toxicology of mycotoxins.

Crit. Rev. Toxicol. 14(2) , 99-132, (1985)

Mycotoxin problems are one of great concern to health scientists. Toxic fungal metabolites such as aflatoxins, trichothecenes, zearalenone and others are contaminated in our environments and induce various diseases. In this manuscript, the author will summari...