Aminoguanidine bicarbonate

Aminoguanidine bicarbonate Structure
Aminoguanidine bicarbonate structure
Common Name Aminoguanidine bicarbonate
CAS Number 2582-30-1 Molecular Weight 135.102
Density 1,6 g/cm3 Boiling Point 422.4ºC at 760 mmHg
Molecular Formula C2H8N4O3 Melting Point 170-172 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 209.3ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells.

Nucleic Acid Ther. 25 , 121-9, (2015)

Covalent binding of squalene to siRNA has already been shown to be an interesting way of delivering siRNA in vivo. Whether squalene derivatives could also be used to deliver siRNA in cells without covalent binding similar to usual transfection with cationic l...

Spermine and aminoguanidine protect cells from chromosome aberrations induced by adenovirus during the G2 phase of the cell cycle.

Chromosoma 84(4) , 571-83, (1982)

Adenovirus uncouples DNA replication from polyamine biosynthesis and causes chromosome aberrations in rodent cells. Addition of polyamines protected infected cells from this chromosome damage. Spermine was the only individual polyamine which protected. The di...

Reversal by aminoguanidine of the inhibition of proliferation of human fibroblasts by spermidine and spermine.

Chem. Biol. Interact. 22(1) , 91-8, (1978)

The inhibitory effect of the polyamines, spermidine and spermine, on the proliferation of human fibroblasts in culture was found to be reversed by the addition of aminoguanidine (AM), a specific and highly effective inhibitor of diamine oxidase (DAO) present ...