Testosterone-d3

Testosterone-d3 Structure
Testosterone-d3 structure
Common Name Testosterone-d3
CAS Number 77546-39-5 Molecular Weight 291.44300
Density 1.134 g/cm3 Boiling Point 432.925ºC at 760 mmHg
Molecular Formula C19H25D3O2 Melting Point 148-150ºC
MSDS Chinese USA Flash Point 5ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

High throughput quantification of prohibited substances in plasma using thin film solid phase microextraction.

J. Chromatogr. A. 1374 , 40-9, (2014)

Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matri...

Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo.

J. Steroid Biochem. Mol. Biol. 143 , 19-28, (2014)

Castration-resistant prostate cancer (CRPC) remains largely dependent on androgen receptor (AR). Residual tissue androgens are consistently detected within CRPC tumors and play a critical role in facilitating AR-mediated signaling pathways which lead to disea...

Assessment of testicular corticosterone biosynthesis in adult male rats.

PLoS ONE 10(2) , e0117795, (2015)

Corticosterone is synthesized in the adrenal glands and is circulated throughout the body to perform regulatory functions in various tissues. The testis is known to synthesize and secrete testosterone and other androgens. We developed an accurate method to me...

Quantification of endogenous metabolites by the postcolumn infused-internal standard method combined with matrix normalization factor in liquid chromatography-electrospray ionization tandem mass spectrometry.

J. Chromatogr. A. 1375 , 62-8, (2014)

Quantification of endogenous metabolites has enabled the discovery of biomarkers for diagnosis and provided for an understanding of disease etiology. The standard addition and stable isotope labeled-internal standard (SIL-IS) methods are currently the most wi...

An LC-MS/MS method for the simultaneous determination of goserelin and testosterone in rat plasma for pharmacokinetic and pharmacodynamic studies.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 965 , 183-9, (2014)

A liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method was developed, using testosterone-d3 as a surrogate analyte, for the simultaneous quantification of goserelin and testosterone in rat plasma. According to this meth...

A critical evaluation of salivary testosterone as a method for the assessment of serum testosterone.

Steroids 86 , 5-9, (2014)

Although salivary testosterone (T) is often used in clinical studies accuracy is mostly questionable. State of the art data for men is sparse and for women absent. Our objective was to perform a critical evaluation of salivary T (Sal-T) as a method for indire...

Strategic use of anti-GnRH vaccine allowing selection of breeding boars without adverse effects on reproductive or production performances.

Theriogenology 85 , 476-82, (2016)

Boar stations raise only entire male pigs for selection as reproductive boars, but the majority of them will fail the selection process, ending at slaughter with a high risk of boar tainted meat. The aim of this study was to investigate whether a single dose ...