Farnesylacetone
Farnesylacetone structure
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Common Name | Farnesylacetone | ||
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| CAS Number | 762-29-8 | Molecular Weight | 262.43000 | |
| Density | 0.88 | Boiling Point | 372.8ºC at 760 mmHg | |
| Molecular Formula | C18H30O | Melting Point | 80.5-81.5 °C | |
| MSDS | Chinese USA | Flash Point | 140.4ºC | |
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Chemical composition of the leaf oil of Actephila excelsa from Vietnam..
Nat. Prod. Commun. 9(9) , 1359-60, (2014) Fresh leaves of Actephila excelsa (Dazl.) Muell. from Vietnam were steam distilled to produce an oil in a yield of 0.15% (v/w). The essential oil was analyzed by a combination of capillary gas chromatography-flame ionization detection (GC-FID) and gas chromat... |
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Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke.
Bioorg. Med. Chem. 14(10) , 3392-8, (2006) It is well established that tobacco smokers have reduced levels of monoamine oxidase activities both in the brain and peripheral organs. Furthermore, extensive evidence suggests that smokers are less prone to develop Parkinson's disease. These facts, plus the... |
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Farnesylacetone, a sesquiterpenic hormone of Crustacea, inhibits electron transport in isolated rat liver mitochondria.
Biol. Cell 67(2) , 141-6, (1989) Farnesylacetone (C18 H30 0) is a male hormone extracted from the androgenic gland of crab, Carcinus maenas. Appropriate enzymatic assays, as well as spectrophotometric studies, indicate that micromolar concentrations of farnesylacetone interact with the elect... |
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5E- and 5Z-farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers.
Vascul. Pharmacol. 58(4) , 299-306, (2013) A specific blocker of L-type Ca(2+) channels may be useful in decreasing arterial tone by reducing the open-state probability of L-type Ca(2+) channels. The aim of the present study was to evaluate the farnesylacetones, which are major active constituents of ... |
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Modulation of membrane fluidity and lipidic metabolism in transformed rat fibroblasts induced by the sesquiterpenic hormone farnesylacetone.
Cytometry 19(3) , 217-25, (1995) Farnesylacetone is a natural terpene extracted from androgenic glands of the crustacean Carcinus maenas and is capable of inhibiting proliferation, notably in transformed mammalian cells. Flow cytometry with three lipophilic probes, diphenylhexatriene, trimet... |
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Inhibition of transmethylases by unsaturated carbonyl derivatives.
Naturwissenschaften 67(12) , 607-8, (1980)
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Comparative effect of farnesylacetone on macromolecular synthesis in gonads of crustaceans.
Gen. Comp. Endocrinol. 54(3) , 462-8, (1984) Farnesylacetone, a molecule isolated from the androgenic glands of Carcinus maenas, inhibits vitellogenesis in the ovaries. Here the effect of farnesylacetone on protein and RNA synthesis in cultured organs is described. Both leucine and uridine incorporation... |
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Cholinesterase inhibitory activity of two farnesylacetone derivatives from the brown alga Sargassum sagamianum.
Arch. Pharm. Res. 26(10) , 796-9, (2003) Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea. Compounds 1 and 2 were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione and (5E,9E,13E)-6,10,4-trimethy... |
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Vasodilatation effect of farnesylacetones, active constituents of Sargassum siliquastrum, on the basilar and carotid arteries of rabbits.
Bioorg. Med. Chem. Lett. 18(24) , 6324-6, (2008) Two farnesylacetones, 311 and 312, major active constituents of Sargassum siliquastrum collected from the coast of the East Sea in Korea, showed a moderate vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with farnesylacetones 31... |
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Substrate specificity of undecaprenyl pyrophophate synthetase from Lactobacillus plantarum. Baba T and Allen Jr CA.
Biochemistry 17(26) , 5598-5604, (1978)
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