trimipramine
trimipramine structure
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Common Name | trimipramine | ||
|---|---|---|---|---|
| CAS Number | 739-71-9 | Molecular Weight | 294.43400 | |
| Density | 0.9912 (rough estimate) | Boiling Point | 426.2°C (rough estimate) | |
| Molecular Formula | C20H26N2 | Melting Point | 45° | |
| MSDS | N/A | Flash Point | 9℃ | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Evaluation of the matrix effect of different sample matrices for 33 pharmaceuticals by post-column infusion.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1000 , 84-94, (2015) Matrix effects that occur during quantitative measurement by liquid chromatography mass spectrometry specifically when using electrospray ionization are a widely recognized phenomenon. Sample matrix compounds affect the ionization process of the target analyt... |
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Antidepressants for patients with tinnitus.
Cochrane Database Syst. Rev. 9 , CD003853, (2012) This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2006 and previously updated in 2009.Tinnitus is described as the perception of sound or noise in the absence of real acoustic stimulation. It has been compared with chr... |
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Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center.
Clin. Toxicol. (Phila.) 52(6) , 629-34, (2014) Seizures during intoxications with pharmaceuticals are a well-known complication. However, only a few studies report on drugs commonly involved and calculate the seizure potential of these drugs.To identify the pharmaceutical drugs most commonly associated wi... |
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FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
Am. Fam. Physician 84(9) , 1-2, (2011)
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Determination of imipramine and trimipramine by capillary electrophoresis with electrochemiluminescence detection.
Talanta 83(5) , 1376-80, (2011) The tricyclic antidepressants (TCA) imipramine (Imi) and trimipramine (Tri) were successfully analyzed by capillary electrophoresis (CE) coupling with Tris(2,2-bipyridyl) ruthenium(II)-based (Ru(bpy)(3)(2+)) end-column electrochemiluminescence (ECL) detection... |
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Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
Drug Metab. Dispos. 38(5) , 863-70, (2010) The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50))... |
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Radiopaque stomach contents in postmortem CT in suicidal oral medication intoxication: report of three cases.
J. Forensic Leg. Med. 17(3) , 164-8, (2010) In clinical medicine, plane radiography is used for detecting the remains of medications in the stomach in oral medication intoxication cases. Since postmortem computed tomography (CT), performed prior to autopsy, is currently intensively entering the forensi... |
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Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters.
Psychopharmacology 217(2) , 289-95, (2011) The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure.The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the... |
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The effect of trimipramine on dream recall and dream emotions in depressive outpatients.
Psychiatry Res. 167(3) , 279-86, (2009) Trimipramine is a sedating tricyclic antidepressant which is not only effective in the treatment of depression but also in primary insomnia. In contrast to most other antidepressants, trimipramine does not affect rapid eye movement sleep. In a large sample of... |
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Metabolism in adipose tissue in response to citalopram and trimipramine treatment--an in situ microdialysis study.
J. Psychiatr. Res. 42(7) , 578-86, (2008) The intake of antidepressants is often accompanied by weight gain. Antidepressants may influence lipid and carbohydrate metabolism that can result in metabolic changes and obesity. We investigated the effect of citalopram and trimipramine on interstitial glyc... |