Thiophane
Thiophane structure
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Common Name | Thiophane | ||
|---|---|---|---|---|
| CAS Number | 110-01-0 | Molecular Weight | 88.171 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 121.5±8.0 °C at 760 mmHg | |
| Molecular Formula | C4H8S | Melting Point | -96 °C | |
| MSDS | Chinese USA | Flash Point | 12.8±0.0 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Synthesis and evaluation of glycopolymeric decorated gold nanoparticles functionalized with gold-triphenyl phosphine as anti-cancer agents.
Biomacromolecules 15(10) , 3802-10, (2014) In this study, statistical glyco-dithiocarbamate (DTC) copolymers were synthesized by reversible addition-fragmentation chain transfer polymerization (RAFT) and subsequently used to prepare glyconanoparticles and conjugated glyconanoparticles with the antican... |
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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the... |
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Interactions of multitargeted kinase inhibitors and nucleoside drugs: Achilles heel of combination therapy?
J. Chromatogr. A. 1421 , 154-61, (2015) Multitargeted tyrosine kinase inhibitors (TKI) axitinib, pazopanib, and sunitinib are used to treat many solid tumors. Combination trials of TKIs with gemcitabine, a nucleoside anticancer drug, in pancreas, renal, lung, ovarian, and other malignancies resulte... |
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Targeting the Proangiogenic VEGF-VEGFR Protein-Protein Interface with Drug-like Compounds by In Silico and In Vitro Screening
Chem. Biol. 18(12) , 1631-9, (2011) Protein-protein interactions play a central role in medicine, and their modulation with small organic compounds remains an enormous challenge. Because it has been noted that the macromolecular complexes modulated to date have a relatively pronounced binding c... |
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[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis].
Eksp. Klin. Farmakol. 74(8) , 37-40, (2011) A hepatoprotective effect of thiophan was studied on the model of carbon tetrachloride-induced hepatitis in rats. Therapeutic administration of thiophan repairs the antitoxic function of liver, normalizes cytolysis marker activity, and improves the synthetic ... |
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[Pharmacological correction of the cytogenetic effects of cisplatin].
Eksp. Klin. Farmakol. 73(10) , 37-9, (2010) Beginning with the first hours of experiments, cisplatin evoked an increase of chromosomal aberrations in CBA/CaLac bone marrow cells. Significant increase of structural infringements of chromosomes due to chromatid breaks was revealed in metaphase plates of ... |
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[Hemorheological effects of thiophane on tetrachloromethane induced hepatic damage].
Eksp. Klin. Farmakol. 73(8) , 32-4, (2010) Carbon tetrachloride-induced hepatitis in rats is accompanied by blood hyperviscosity syndrome development. A course intragastric administration of thiophane under these conditions prevents the increase in whole blood viscosity by normalizing the microrheolog... |
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Smell of danger: an analysis of LP-gas odorization.
Am. Ind. Hyg. Assoc. J. 46(3) , 115-26, (1985) LP-gas derives warning properties from the odorants ethyl mercaptan or thiophane. Laboratory tests have implied that the average person has the ability to smell the odors before leaking LP-gas reaches one-fifth its lower limit of flammability. Generally, howe... |
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Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.
Biol. Psychiatry 28(1) , 22-33, (2003) Using purified enzyme preparations, we investigated the actions of angiotensin-converting enzyme, aminopeptidase N, and endopeptidase 24.11 on corticotropin-releasing factor (CRF). The effects of inhibition of these enzymes on CRF action in rat anterior pitui... |
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Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells.
Cell Biochem. Funct. 26(8) , 916-9, (2008) NEP/CALLA or CD10 is an endopeptidase (E.C. 3.4.24.11) that inactivates numerous neuropeptides, including dynorphin. Dynorphin is an endogenous opioid polypeptide that binds to kappa-opioid receptors with greatest affinity. R1.1 mouse thymoma cells highly exp... |