Eksperimental'naia i klinicheskaia farmakologiia 2011-01-01

[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis].

V I Smol'iakova, M B Plotnikov, G A Chernysheva, I S Ivanov, A E Prosenko, N V Kandalintseva

Index: Eksp. Klin. Farmakol. 74(8) , 37-40, (2011)

Full Text: HTML

Abstract

A hepatoprotective effect of thiophan was studied on the model of carbon tetrachloride-induced hepatitis in rats. Therapeutic administration of thiophan repairs the antitoxic function of liver, normalizes cytolysis marker activity, and improves the synthetic function of liver and the carbohydrate and lipid metabolism. The hepatoprotective activity of thiophan is similar to effect of silimarin.