(3-Chlorophenyl)methanamine

(3-Chlorophenyl)methanamine Structure
(3-Chlorophenyl)methanamine structure
Common Name (3-Chlorophenyl)methanamine
CAS Number 4152-90-3 Molecular Weight 141.598
Density 1.2±0.1 g/cm3 Boiling Point 225.3±0.0 °C at 760 mmHg
Molecular Formula C7H8ClN Melting Point N/A
MSDS Chinese USA Flash Point 98.3±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors.

Bioorg. Med. Chem. Lett. 13(12) , 1981-4, (2003)

Dihydroquinolines with aminoalkyl side chains have been synthesized and have been shown to be potent n-NOS inhibitors. A marked selectivity versus e-NOS of up to approximately 300-fold was observed, whereas i-NOS was moderately inhibited.

Rates of reaction of benzylamines with 1-chloro-2, 4-dinitrobenzene and with toluene-p-sulphonyl chloride.

J. Chem. Soc. B: Phys. Org. , 466-468, (1966)