4,4′-bis(N-carbazolyl)biphenyl
4,4′-bis(N-carbazolyl)biphenyl structure
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Common Name | 4,4′-bis(N-carbazolyl)biphenyl | ||
|---|---|---|---|---|
| CAS Number | 58328-31-7 | Molecular Weight | 484.589 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 700.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H24N2 | Melting Point | 281-285 °C | |
| MSDS | Chinese USA | Flash Point | 377.6±32.9 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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The PHD finger of p300 influences its ability to acetylate histone and non-histone targets.
J. Mol. Biol. 426(24) , 3960-72, (2014) In enzymes that regulate chromatin structure, the combinatorial occurrence of modules that alter and recognise histone modifications is a recurrent feature. In this study, we explored the functional relationship between the acetyltransferase domain and the ad... |
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Ku80 cooperates with CBP to promote COX-2 expression and tumor growth.
Oncotarget 6 , 8046-61, (2015) Cyclooxygenase-2 (COX-2) plays an important role in lung cancer development and progression. Using streptavidin-agarose pulldown and proteomics assay, we identified and validated Ku80, a dimer of Ku participating in the repair of broken DNA double strands, as... |
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CRTC2 and Nedd4 ligase involvement in FSH and TGFβ1 upregulation of connexin43 gap junction.
J. Mol. Endocrinol. 55 , 263-75, (2015) The major mission of the ovarian follicle is the timely production of the mature fertilizable oocyte, and this is achieved by gonadotropin-regulated, gap junction-mediated cell-cell communication between the oocyte and surrounding nurturing granulosa cells. W... |
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Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes.
Neurochem. Res. 40 , 2333-47, (2015) Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that plays an important role in multiple sclerosis (MS). However, mechanisms by which CNTF expression could be increased in the brain are poorly understood. Recently we have discovered anti... |
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Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation.
Biochim. Biophys. Acta 1852(1) , 34-46, (2015) Glomerulosclerosis and interstitial fibrosis represent the key events in development of diabetic nephropathy (DN), with connective tissue growth factor (CTGF), plasminogen activator inhibitor-1 (PAI-1) and fibronectin 1 (FN-1) playing important roles in these... |
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A simultaneous extraction method for organophosphate, pyrethroid, and neonicotinoid insecticides in aqueous samples.
Arch. Environ. Contam. Toxicol. 68(4) , 745-56, (2015) A method was developed for the extraction and analysis of 2 organophosphate, 8 pyrethroid, and 5 neonicotinoid insecticides from the same water sample. A salted liquid-liquid extraction (LLE) was optimized with a solid-phase extraction (SPE) step that separat... |
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A Rhesus Rhadinovirus Viral Interferon (IFN) Regulatory Factor Is Virion Associated and Inhibits the Early IFN Antiviral Response.
J. Virol. 89 , 7707-21, (2015) The interferon (IFN) response is the earliest host immune response dedicated to combating viral infection. As such, viruses have evolved strategies to subvert this potent antiviral response. Two closely related gammaherpesviruses, Kaposi's sarcoma-associated ... |
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Gallic Acid Decreases Inflammatory Cytokine Secretion Through Histone Acetyltransferase/Histone Deacetylase Regulation in High Glucose-Induced Human Monocytes.
J. Med. Food 18 , 793-801, (2015) Hyperglycemia contributes to diabetes and several diabetes-related complications. Gallic acid is a polyhydroxy phenolic compound found in various natural products. In this study, we investigated the effects and mechanism of gallic acid on proinflammatory cyto... |
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Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development.
J. Neurosci. 35 , 15875-93, (2015) The oligodendrocyte transcription factor Olig1 is critical for both oligodendrocyte development and remyelination in mice. Nuclear to cytoplasmic translocation of Olig1 protein occurs during brain development and in multiple sclerosis, but the detailed molecu... |
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The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.
Sci. Signal. 8 , ra120, (2015) Cortactin is an F-actin-binding protein that localizes to the cell cortex, where the actin remodeling that is required for cell migration occurs. We found that cortactin shuttled between the cytoplasm and the nucleus under basal conditions. We identified Kelc... |