Bisoprolol
Bisoprolol structure
|
Common Name | Bisoprolol | ||
|---|---|---|---|---|
| CAS Number | 66722-44-9 | Molecular Weight | 325.443 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 445.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H31NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 222.9±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
High throughput quantification of prohibited substances in plasma using thin film solid phase microextraction.
J. Chromatogr. A. 1374 , 40-9, (2014) Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matri... |
|
|
Enantiomeric fraction evaluation of pharmaceuticals in environmental matrices by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1363 , 226-235, (2014) The interest for environmental fate assessment of chiral pharmaceuticals is increasing and enantioselective analytical methods are mandatory. This study presents an enantioselective analytical method for the quantification of seven pairs of enantiomers of pha... |
|
|
β-Blockers promote angiogenesis in the mouse aortic ring assay.
J. Cardiovasc. Pharmacol. 64(1) , 21-7, (2014) Recent results indicate that the reduction of β-adrenergic signaling impairs angiogenesis under ischemic conditions. Because angiogenesis may occur in the absence of ischemia, it remains to be determined whether and how β-adrenergic signaling regulates angiog... |
|
|
Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses.
FASEB J. 25 , 4486-97, (2011) β-Adrenoceptor antagonists differ in their degree of partial agonism. In vitro assays have provided information on ligand affinity, selectivity, and intrinsic efficacy. However, the extent to which these properties are manifest in vivo is less clear. Consciou... |
|
|
Effects of bisoprolol and cilazapril on the central retinal artery blood flow in patients with essential hypertension--preliminary results.
Ups. J. Med. Sci. 115(4) , 249-52, (2010) A growing body of evidence suggests that effective blood pressure reduction may inhibit the progression of microvascular damage in patients with essential arterial hypertension. However, the potential influence of anti-hypertensive drugs on ocular circulation... |
|
|
Effect of liandouqingmai recipe on quality of life and inflammatory reactions of patients with coronary heart disease.
J. Tradit. Chin. Med. 34(5) , 539-43, (2014) To observe the effect of Liandouqingmai recipe (Chinese herbal medicine compound preparation) on the quality of life (QOL) and inflammatory reaction of patients with coronary heart disease (CHD).A total of 101 CHD patients were randomized into two groups: tre... |
|
|
Bioequivalence study of two formulations of bisoprolol fumarate film-coated tablets in healthy subjects.
Drug Des. Devel. Ther. 6 , 311-6, (2012) The present study was conducted to compare the bioavailability of two bisoprolol fumarate 5 mg film-coated tablet formulations (test and reference formulations).This study was a randomized, single-blind, two-period, two-sequence crossover study that included ... |
|
|
Biowaiver monograph for immediate-release solid oral dosage forms: bisoprolol fumarate.
J. Pharm. Sci. 103(2) , 378-91, (2014) Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing bisoprolol as the sole active pharmaceutical ingredient (API) are reviewed. Bisopro... |
|
|
The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor.
Naunyn Schmiedebergs Arch. Pharmacol. 384 , 71-91, (2011) The X-ray crystal structure of the turkey β-adrenoceptor has recently been determined. However, mutations were introduced into the native receptor that was essential for structure determination. These may cause alterations to the receptor pharmacology. It is ... |
|
|
Acute wounding alters the beta2-adrenergic signaling and catecholamine synthetic pathways in keratinocytes.
J. Invest. Dermatol. 134(8) , 2258-66, (2014) Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathwa... |