Bisoprolol
Bisoprolol structure
|
Common Name | Bisoprolol | ||
|---|---|---|---|---|
| CAS Number | 66722-44-9 | Molecular Weight | 325.443 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 445.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H31NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 222.9±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of BisoprololBisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. |
| Name | bisoprolol |
|---|---|
| Synonym | More Synonyms |
| Description | Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. |
|---|---|
| Related Catalog | |
| Target |
β1-adrenergic receptor[1] |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 445.0±45.0 °C at 760 mmHg |
| Molecular Formula | C18H31NO4 |
| Molecular Weight | 325.443 |
| Flash Point | 222.9±28.7 °C |
| Exact Mass | 325.225311 |
| PSA | 59.95000 |
| LogP | 2.14 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.500 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| RTECS | UB8380000 |
| HS Code | 2922509090 |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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High throughput quantification of prohibited substances in plasma using thin film solid phase microextraction.
J. Chromatogr. A. 1374 , 40-9, (2014) Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are meth... |
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Enantiomeric fraction evaluation of pharmaceuticals in environmental matrices by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1363 , 226-235, (2014) The interest for environmental fate assessment of chiral pharmaceuticals is increasing and enantioselective analytical methods are mandatory. This study presents an enantioselective analytical method ... |
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β-Blockers promote angiogenesis in the mouse aortic ring assay.
J. Cardiovasc. Pharmacol. 64(1) , 21-7, (2014) Recent results indicate that the reduction of β-adrenergic signaling impairs angiogenesis under ischemic conditions. Because angiogenesis may occur in the absence of ischemia, it remains to be determi... |
| 1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol |
| (±)-1-[p-(2-Isopropoxyethoxymethyl)phenoxy]-3-(isopropylamino)-2-propanol |
| 1-(propan-2-ylamino)-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol |
| Bisoprolol |
| 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol |
| 2-Propanol, 1-(4-((2-(1-methylethoxy)ethoxy)methyl)phenoxy)-3-((1-methylethyl)amino)- |
| MFCD00865795 |
| 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol |
| (±)-1-[[a-(2-Isopropoxyethoxy)-p-tolyl]oxy]-3-(isopropylamino)-2-propanol |
| 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol |
| 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol |
| 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)-2-propanol |
| 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]- |