Pentamidine isethionate
Pentamidine isethionate structure
|
Common Name | Pentamidine isethionate | ||
|---|---|---|---|---|
| CAS Number | 140-64-7 | Molecular Weight | 592.683 | |
| Density | N/A | Boiling Point | 539.4ºC at 760mmHg | |
| Molecular Formula | C23H36N4O10S2 | Melting Point | 188-194 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 280ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis.
PLoS Pathog. 11 , e1004942, (2015) African trypanosomiasis is a deadly neglected disease caused by the extracellular parasite Trypanosoma brucei. Current therapies are characterized by high drug toxicity and increasing drug resistance mainly associated with loss-of-function mutations in the tr... |
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Anti-leishmanial lindenane sesquiterpenes from Hedyosmum angustifolium.
Planta Med. 76 , 365-8, (2010) The aim of this work is the isolation of anti-leishmanial compounds from the ethyl acetate extracts of the bark of HEDYOSMUM ANGUSTIFOLIUM. We have successfully isolated and characterized five sesquiterpenes: one new compound (oxyonoseriolide, 1), one compoun... |
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Pentamidine is an N-methyl-D-aspartate receptor antagonist and is neuroprotective in vitro.
J. Neurosci. 12 , 970, (1992) Acquired immunodeficiency syndrome (AIDS) is frequently associated with dementia. The wide spectrum of neurological abnormalities associated with this dementia may involve a neurotoxin that activates the NMDA subtype of glutamate receptor in neurons. We have ... |