2H-Purine-2-thione,3,9-dihydro-

2H-Purine-2-thione,3,9-dihydro- Structure
2H-Purine-2-thione,3,9-dihydro- structure
Common Name 2H-Purine-2-thione,3,9-dihydro-
CAS Number 28128-19-0 Molecular Weight 152.17700
Density 1.82g/cm3 Boiling Point 498.6ºC at 760mmHg
Molecular Formula C5H4N4S Melting Point N/A
MSDS Chinese USA Flash Point 255.4ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Analysis of phenolic compounds in the dissolved and suspended phases of Lake Balaton water by gas chromatography-tandem mass spectrometry.

Environ. Sci. Pollut. Res. Int. 22 , 11966-74, (2015)

As a novel approach to characterize the phenolic pollutants of Lake Balaton (Central Europe, western Hungary), 26 endocrine disrupting phenols (chlorophenols, nitrophenols, alkylphenols, triclosan, bisphenol-A) were quantified in dissolved and suspended parti...

Rate Coefficients for the Gas-Phase Reactions of Hydroxyl Radicals with a Series of Methoxylated Aromatic Compounds.

J. Phys. Chem. A 119 , 6179-87, (2015)

Rate coefficients for the reactions of hydroxyl radicals (OH) with a series of oxygenated aromatics (two methoxybenzene and five methoxyphenol isomers) have been obtained using the relative kinetic method in 1080 and 480 L photoreactors at the University of W...

6-Mercaptopurine decreases the Bcl-2/Bax ratio and induces apoptosis in activated splenic B lymphocytes.

Mol. Pharmacol. 51 , 414-421, (1997)

6-Mercaptopurine and related purine antimetabolites are used in the treatment of several B cell disorders. These drugs inhibited the proliferation of mature splenic B cells after being triggered with polyclonal mitogens. In addition to the antiproliferative e...

Kinetics of oxidation of aliphatic and aromatic thiols by myeloperoxidase compounds I and II.

FEBS Lett. 443 , 290-296, (1999)

Myeloperoxidase (MPO) is the most abundant protein in neutrophils and plays a central role in microbial killing and inflammatory tissue damage. Because most of the non-steroidal anti-inflammatory drugs and other drugs contain a thiol group, it is necessary to...

Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different.

Biochemistry. (Mosc.) 72 , 170-177, (2007)

Xanthine oxidase-catalyzed hydroxylation reactions of the anticancer drug 6-mercaptopurine (6-MP) and its analog 2-mercaptopurine (2-MP) as well as 6-thioxanthine (6-TX) and 2-thioxanthine (2-TX) have been studied using UV-spectroscopy, high pressure liquid c...