Byakangelicin
Byakangelicin structure
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Common Name | Byakangelicin | ||
|---|---|---|---|---|
| CAS Number | 482-25-7 | Molecular Weight | 334.321 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 571.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C17H18O7 | Melting Point | 123-124℃ | |
| MSDS | Chinese USA | Flash Point | 299.4±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Simultaneous determination of byak-angelicin and oxypeucedanin hydrate in rat plasma by column-switching high-performance liquid chromatography with ultraviolet detection.
J. Chromatogr. B. Biomed. Sci. Appl. 753(2) , 309-14, (2001) A simple and sensitive column-switching HPLC method was developed for the simultaneous determination of two furocoumarin compounds, byak-angelicin and oxypeucedanin hydrate, which are the main components of hot water extract of Angelica dahurica root (AE), in... |
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[Studies on quality standards of radix Angelicae dahuricae].
Zhongguo Zhong Yao Za Zhi 29(7) , 654-7, (2004) To work out a qualitay standard of Radix Angelicae dahuricae.TLC and HPLC were adopted.Four coumerin compounds were identified by TLC, and the contents of two compounds were determined by HPLC.Imperatorin, isoimperatorin, byakangelicin and oxypeucedaninhydrat... |
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Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells.
Planta Med. 68(5) , 463-4, (2002) Fractionation of the MeOH extract of Angelica dahurica Benth et Hook resulted in the isolation of six furocoumarins, imperatorin (1), isoimperatorin (2), (+/-)-byakangelicol (3), (+)-oxypeucedanin (4), (+)-byakangelicin (5), and (+)-aviprin (6). Among these, ... |
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High-performance liquid chromatographic method for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma.
J. Pharm. Biomed. Anal. 44(1) , 166-72, (2007) A high-performance liquid chromatographic method was developed and validated for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma. The coumari... |
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Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes.
Br. J. Pharmacol. 162(2) , 441-51, (2011) Byakangelicin is found in extracts of the root of Angelica dahurica, used in Korea and China as a traditional medicine to treat colds, headache and toothache. As byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogeno... |
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Crystal structure of byakangelicin (C17H18O7).
Arch. Pharm. Res. 25(3) , 275-9, (2002) The crystal structure of byakangelicin, one of furanocoumarin aldose reductase inhibitors, was determined by X-ray diffraction method. The crystal is triclinic, with a = 8.114(1), b = 10.194(1), c = 11.428(1)A, a = 111.50(1), beta= 95.57(1), gamma = 112.52(1)... |