Byakangelicin structure
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Common Name | Byakangelicin | ||
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CAS Number | 482-25-7 | Molecular Weight | 334.321 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 571.5±50.0 °C at 760 mmHg | |
Molecular Formula | C17H18O7 | Melting Point | 123-124℃ | |
MSDS | Chinese USA | Flash Point | 299.4±30.1 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of ByakangelicinByakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects[1]. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones[2]. |
Name | Byakangelicin |
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Synonym | More Synonyms |
Description | Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects[1]. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones[2]. |
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Related Catalog | |
Target |
PXR[2] |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 571.5±50.0 °C at 760 mmHg |
Melting Point | 123-124℃ |
Molecular Formula | C17H18O7 |
Molecular Weight | 334.321 |
Flash Point | 299.4±30.1 °C |
Exact Mass | 334.105255 |
PSA | 102.27000 |
LogP | 1.62 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.613 |
Storage condition | ?20°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Phrases | 22-36/37/38 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
Simultaneous determination of byak-angelicin and oxypeucedanin hydrate in rat plasma by column-switching high-performance liquid chromatography with ultraviolet detection.
J. Chromatogr. B. Biomed. Sci. Appl. 753(2) , 309-14, (2001) A simple and sensitive column-switching HPLC method was developed for the simultaneous determination of two furocoumarin compounds, byak-angelicin and oxypeucedanin hydrate, which are the main compone... |
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[Studies on quality standards of radix Angelicae dahuricae].
Zhongguo Zhong Yao Za Zhi 29(7) , 654-7, (2004) To work out a qualitay standard of Radix Angelicae dahuricae.TLC and HPLC were adopted.Four coumerin compounds were identified by TLC, and the contents of two compounds were determined by HPLC.Imperat... |
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Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells.
Planta Med. 68(5) , 463-4, (2002) Fractionation of the MeOH extract of Angelica dahurica Benth et Hook resulted in the isolation of six furocoumarins, imperatorin (1), isoimperatorin (2), (+/-)-byakangelicol (3), (+)-oxypeucedanin (4)... |
7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy- |
9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g]chromen-7-one |