8-O-乙酰哈巴苷

更新时间：2025-08-21 14:21:19

8-O-乙酰哈巴苷结构式	常用名	8-O-乙酰哈巴苷	英文名	8-O-Acetylharpagide
	CAS号	6926-14-3	分子量	406.382
	密度	1.6±0.1 g/cm3	沸点	607.2±55.0 °C at 760 mmHg
	分子式	C₁₇H₂₆O₁₁	熔点	227-229℃
	MSDS	美版	闪点	215.9±25.0 °C

8-O-乙酰哈巴苷用途

8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜化合物,具有抗肿瘤、抗病毒、抗菌和抗炎活性。8-O-Acetylharpagide 对豚鼠离体平滑肌也有生物活性。

中文名	乙酰哈巴苷
英文名	8-O-Acetylharpagide
中文别名	8-O-乙酰哈巴苷
英文别名	更多

描述	8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜化合物,具有抗肿瘤、抗病毒、抗菌和抗炎活性。8-O-Acetylharpagide 对豚鼠离体平滑肌也有生物活性。
相关类别	研究领域 >> 癌症研究领域 >> 感染信号通路 >> 其他 >> 其他研究领域 >> 炎症/免疫
参考文献	[1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8. [2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8.

描述

相关类别

研究领域 >> 癌症

研究领域 >> 感染

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

参考文献

[1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8.

[2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8.

密度	1.6±0.1 g/cm3
沸点	607.2±55.0 °C at 760 mmHg
熔点	227-229℃
分子式	C₁₇H₂₆O₁₁
分子量	406.382
闪点	215.9±25.0 °C
精确质量	406.147522
PSA	175.37000
LogP	-3.48
InChIKey	CAFTUQNGDROXEZ-XBDCZORHSA-N
SMILES	CC(=O)OC1(C)CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12
蒸汽压	0.0±3.9 mmHg at 25°C
折射率	1.624
储存条件	?20°C

安全声明 (欧洲)	24/25
危险品运输编码	NONH for all modes of transport

[Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens extract in beagle dog].

Zhongguo Zhong Yao Za Zhi 38(12) , 2015-8, (2013)

8-O-acetylharpagide and harpagide are two kinds of effective component of Ajuga decumbens extract. A sensitive LC-MS/MS method has been established for pharmacokinetics of 8-O-acetylharpagide and harp...

[Determination of acetylharpagide in Ajuga decumbens by HPLC].

Zhongguo Zhong Yao Za Zhi 31(4) , 289-90, (2006)

To establish a method of the quantitative determination of acetylharpagide in Ajuga decumbens.The chromatographic conditions were as follows: a Phenomenex Luna C18 column was used, the mobile phase wa...

[Studies on chemical constituents of Galeopsis bifida].

Zhongguo Zhong Yao Za Zhi 27(3) , 206-8, (2002)

To investigate the chemical constituents of Galeopsis bifida.Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chem...

β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-1-yl

6-Thio-8-propylthiotheophylline

(1S,4aS,5R,7S,7aS)-1-(β-D-Glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl acetate

8-O-acetyl-harpagide

Harpagide 7-acetyl

Uric acid,1,3-dimethyl-8-propylthio-6-thio

8-n-Propylthio-6-thiotheophyllin