甲醇中喷布特罗溶液标准物质

更新时间：2025-08-21 10:04:41

甲醇中喷布特罗溶液标准物质结构式	常用名	甲醇中喷布特罗溶液标准物质	英文名	Penbutolol sulfate
	CAS号	38363-32-5	分子量	340.47
	密度	N/A	沸点	438.2ºC at 760mmHg
	分子式	C₁₈H₂₉NO_2.1/₂H₂O₄S	熔点	216-218℃ (Decomposition)
	MSDS	N/A	闪点	218.8ºC

甲醇中喷布特罗溶液标准物质用途

Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。

中文名	硫酸喷布洛尔
英文名	Penbutolol sulfate
中文别名	喷布洛尔硫酸盐
英文别名	更多

描述	Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体研究领域 >> 心血管疾病

沸点	438.2ºC at 760mmHg
熔点	216-218℃ (Decomposition)
分子式	C₁₈H₂₉NO_2.1/₂H₂O₄S
分子量	340.47
闪点	218.8ºC
PSA	41.49000
LogP	3.86290
InChIKey	FEDSNBHHWZEYTP-ZFQYHYQMSA-N
SMILES	CC(C)(C)NCC(O)COc1ccccc1C1CCCC1.CC(C)(C)NCC(O)COc1ccccc1C1CCCC1.O=S(=O)(O)O
储存条件	2-8°C

甲醇中喷布特罗溶液标准物质毒性英文版

危害码 (欧洲)	Xn
危险品运输编码	NONH for all modes of transport

5-HT receptor subtypes involved in the spinal antinociceptive effect of acetaminophen in rats.

Eur. J. Pharmacol. 432(1) , 1-7, (2001)

The present study was designed to investigate which subtype of spinal 5-HT receptors were involved in acetaminophen-induced antinociception using the paw-pressure test. Propacetamol (prodrug of acetam...

Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor.

Brain Res. 835(2) , 224-8, (1999)

Serotonin (5-hydroxytryptamine, 5-HT) autoreceptors may desensitize during prolonged administration of antidepressant drugs. If autoreceptors desensitize, their inhibitory influence on extracellular 5...

Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain.

J. Neurochem. 75(2) , 755-62, (2000)

There is considerable interest in the use of drugs that selectively block presynaptic (somatodendritic) serotonin 5-HT(1A) receptors for the adjunctive treatment of major depressive disorder. The 5-HT...

Penbutolol Sulfate