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38363-32-5生产厂家

38363-32-5价格

38363-32-5

38363-32-5结构式
38363-32-5结构式
  • 常用中文名:甲醇中喷布特罗溶液标准物质
  • 常用英文名:Penbutolol sulfate
  • CAS号:38363-32-5
  • 分子式:C18H29NO2.1/2H2O4S
  • 分子量:340.47
  • 相关类别: 分析化学 标准品 法医和兽医标准品
  • 发布时间:2018-08-20 20:00:49
  • 更新时间:2024-01-22 17:40:29
  • Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。

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中文名 硫酸喷布洛尔
英文名 Penbutolol sulfate
中文别名 喷布洛尔硫酸盐
英文别名 Penbutolol Sulfate
描述 Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。
相关类别
沸点 438.2ºC at 760mmHg
熔点 216-218℃ (Decomposition)
分子式 C18H29NO2.1/2H2O4S
分子量 340.47
闪点 218.8ºC
PSA 41.49000
LogP 3.86290
储存条件 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA9818700
CAS REGISTRY NUMBER :
38363-32-5
LAST UPDATED :
199606
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C18-H29-N-O2.1/2H2-O4-S
MOLECULAR WEIGHT :
340.47
WISWESSER LINE NOTATION :
L5TJ AR BO1YQ1MX1&1&1 2 &..H2.S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
76 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
860 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1230 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
71 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
405 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
38 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
297 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
17 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
384 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Human Fibroblast
DOSE/DURATION :
50 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,675,1988

危害码 (欧洲) Xn
危险品运输编码 NONH for all modes of transport