3-肟-6,7-二氯-1H-吲哚-2,3-二酮结构式
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常用名 | 3-肟-6,7-二氯-1H-吲哚-2,3-二酮 | 英文名 | NS309 |
|---|---|---|---|---|
| CAS号 | 18711-16-5 | 分子量 | 231.036 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C8H4Cl2N2O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
3-肟-6,7-二氯-1H-吲哚-2,3-二酮用途NS309是钙离子激活的钾离子通道(KCa2和KCa3.1)的阳性调节剂,能增强钙离子的敏感性,对BK通道无活性。 |
| 中文名 | 3-肟-6,7-二氯-1H-吲哚-2,3-二酮 |
|---|---|
| 英文名 | 6,7-dichloro-3-(hydroxyamino)indol-2-one |
| 中文别名 | 6,7-二氯-1H-吲哚-2,3-二酮-3-肟 |
| 英文别名 | 更多 |
| 描述 | NS309是钙离子激活的钾离子通道(KCa2和KCa3.1)的阳性调节剂,能增强钙离子的敏感性,对BK通道无活性。 |
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| 相关类别 | |
| 参考文献 |
| 密度 | 1.8±0.1 g/cm3 |
|---|---|
| 分子式 | C8H4Cl2N2O2 |
| 分子量 | 231.036 |
| 精确质量 | 229.964981 |
| PSA | 61.69000 |
| LogP | 2.66 |
| 折射率 | 1.742 |
| 储存条件 | 2-8℃ |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P261-P305 + P351 + P338 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) | Xi: Irritant; |
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | S26 |
| 危险品运输编码 | NONH for all modes of transport |
| 海关编码 | 2933790090 |
| 海关编码 | 2933790090 |
|---|---|
| 中文概述 | 2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |
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Inactivation of Endothelial Small/Intermediate Conductance of Calcium-Activated Potassium Channels Contributes to Coronary Arteriolar Dysfunction in Diabetic Patients.
J. Am. Heart Assoc. 4 , e002062, (2015) Diabetes is associated with coronary arteriolar endothelial dysfunction. We investigated the role of the small/intermediate (SK(Ca)/IK(Ca)) conductance of calcium-activated potassium channels in diabe... |
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Duration differences of corticostriatal responses in striatal projection neurons depend on calcium activated potassium currents.
Front. Syst. Neurosci. 7 , 63, (2013) The firing of striatal projection neurons (SPNs) exhibits afterhyperpolarizing potentials (AHPs) that determine discharge frequency. They are in part generated by Ca(2+)-activated K(+)-currents involv... |
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Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats.
Eur. J. Pharmacol. 735 , 68-76, (2014) We have analysed the effects of large-conductance calcium-activated potassium channel (BK) stimulation on neurogenic and myogenic contraction of human bladder from healthy subjects and patients with u... |
| 1H-Indole-2,3-dione, 6,7-dichloro-, 3-oxime, (3E)- |
| 6,7-Dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one |
| NS-309 |
| 6,7-dichloro-1H-indole-2,3-dione-3-oxime |
| (3E)-6,7-Dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one |
| 6,7-dichloroisatin 3-oxime |
| 1H-Indole-2,3-dione, 6,7-dichloro-, 3-oxime |
| 6,7-Dichloro-1H-indole-2,3-dione 3-oxime |
| 3-Oxime-6,7-dichloro-1H-indole-2,3-dione |
| NS309 |
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