Ganirelix Acetate

• 常用名: Ganirelix Acetate
• 英文名: Ganirelix Acetate
• CAS号: 129311-55-3
• 分子量: 1690.423
• 密度: N/A
• 沸点: N/A
• 分子式: C₈₄H₁₂₁ClN₁₈O₁₇
• 熔点: N/A
• 闪点: N/A
• 符号: GHS07
• 信号词: Warning

Ganirelix Acetate用途

醋酸甘乃瑞利(Ganirelix醋酸盐,Ganirest)是一种可注射竞争性促性腺激素释放激素(GnRH)拮抗剂。甘乃瑞利醋酸盐直接与内源性分子竞争受体结合,并导致雌二醇水平迅速降低。甘乃瑞利醋酸盐可用于研究卵巢过度刺激综合征(OHSS)[1]。

Ganirelix Acetate名称

• 英文名: Ganirelix acetate

Ganirelix Acetate生物活性

• 描述: 醋酸甘乃瑞利(Ganirelix醋酸盐,Ganirest)是一种可注射竞争性促性腺激素释放激素(GnRH)拮抗剂。甘乃瑞利醋酸盐直接与内源性分子竞争受体结合,并导致雌二醇水平迅速降低。甘乃瑞利醋酸盐可用于研究卵巢过度刺激综合征(OHSS)[1]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> GNRH受体
  研究领域 >> 代谢疾病
• 靶点:

  GnRH[1]

• 参考文献:

  [1]. Gustofson RL, et al. Ganirelix acetate causes a rapid reduction in estradiol levels without adversely affecting oocyte maturation in women pretreated with leuprolide acetate who are at risk of ovarian hyperstimulation syndrome. Hum Reprod. 2006 Nov;21(11):2830-7.

Ganirelix Acetate物理化学性质

• 分子式: C₈₄H₁₂₁ClN₁₈O₁₇
• 分子量: 1690.423
• 精确质量: 1688.884521
• InChIKey: OVBICQMTCPFEBS-SATRDZAXSA-N
• SMILES: CC(=O)O.CC(=O)O.CCNC(=NCCCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1cccnc1)NC(=O)C(Cc1ccc(Cl)cc1)NC(=O)C(Cc1ccc2ccccc2c1)NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN=C(NCC)NCC)C(=O)N1CCCC1C(=O)NC(C)C(N)=O)NCC
• 储存条件: -20°C，密闭，干燥

Ganirelix Acetate安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 危险品运输编码: NONH for all modes of transport

Ganirelix Acetate英文别名

• 56U7906FQW
• D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]- ;L-lysyl-L-prolyl-, acetate (1:2)
• Ganirelix acetate
• UNII:56U7906FQW
• N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D- ;alaninamide acetate (1:2)