6138-56-3

6138-56-3结构式

常用中文名：TRIPELENNAMINE CITRATE
常用英文名：TRIPELENNAMINE CITRATE
CAS号：6138-56-3
分子式：C₂₂H₂₉N₃O₇
分子量：447.48200
相关类别：信号通路 G 蛋白偶联受体/G 蛋白组胺受体
发布时间：2017-02-26 06:48:44
更新时间：2024-01-11 17:49:35
柠檬酸三苯那敏是一种乙二胺衍生物,是一种有效的组胺H1受体拮抗剂。柠檬酸三苯那敏可以减轻由组胺引起的机体过敏反应。柠檬酸三苯那敏可用于研究鼻炎、结膜炎、过敏和过敏反应[1][2][3]。

英文名	N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine,2-hydroxypropane-1,2,3-tricarboxylic acid
英文别名	Pyridine,2-(benzyl(2-(dimethylamino)ethyl)amino)-,citrate (1:1) Pyribenzamine citrate EINECS 228-121-6 Tripelennamine citrate 1,2-Ethanediamine,N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-,2-hydroxy-1,2,3-propanetricarboxylate (1:1)

描述	柠檬酸三苯那敏是一种乙二胺衍生物,是一种有效的组胺H1受体拮抗剂。柠檬酸三苯那敏可以减轻由组胺引起的机体过敏反应。柠檬酸三苯那敏可用于研究鼻炎、结膜炎、过敏和过敏反应[1][2][3]。
相关类别	信号通路 >> 免疫及炎症 >> 组胺受体研究领域 >> 内分泌研究领域 >> 炎症/免疫信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
靶点	H1 Receptor
参考文献	[1]. Manohar M, et al. H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds. J Appl Physiol. 2002 Apr;92(4):1515-23. [2]. Wasfi IA, et al. Comparative disposition of tripelennamine in horses and camels after intravenous administration. J Vet Pharmacol Ther. 2000 Jun;23(3):145-52. [3]. Yeh SY, et al. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39(6):669-76.

REFERENCE :: CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 16,331,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80566 No. of Facilities: 460 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 3946 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80566 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1957 (estimated) No. of Female Employees: 1888 (estimated)