Proinsulin C-Peptide (55-89), human
Proinsulin C-Peptide (55-89), human结构式
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常用名 | Proinsulin C-Peptide (55-89), human | 英文名 | Proinsulin C-Peptide (55-89) human |
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| CAS号 | 11097-48-6 | 分子量 | 3616.99000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C153H259N49O52 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Molecular and cellular effects of C-peptide--new perspectives on an old peptide.
Exp. Diabesity Res. 5 , 15-23, (2004) New results present C-peptide as a biologically active peptide hormone in its own right. Although C-peptide is formed from proinsulin and cosecreted with insulin, it is a separate entity with biochemical and physiological characteristics that differ from thos... |
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Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein.
Diabetologia 53 , 1761-71 , (2010) Endothelial cells (ECs) and smooth muscle cells (SMCs) play key roles in the development of intimal hyperplasia in saphenous vein (SV) bypass grafts. In diabetic patients, insulin administration controls hyperglycaemia but cardiovascular complications remain.... |
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Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide.
J. Biol. Chem. 246 , 1375, (1971)
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Structural features of proinsulin C-peptide oligomeric and amyloid states.
FEBS J. 277 , 3759-3768, (2010) The formation and structure of proinsulin C-peptide oligomers has been investigated by PAGE, NMR spectroscopy and dynamic light scattering. The results obtained show that C-peptide forms oligomers of different sizes, and that their formation and size distribu... |
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N-terminal segment of proinsulin C-peptide active in insulin interaction/desaggregation
Biochem. Biophys. Res. Commun. 403 , 462-467, (2010) Research highlights ► C-peptide fragment interactions with insulin involve the N-terminal part with Glu11. ► Insulin-interacting and membrane-interacting segments of C-peptide are different. ► Oligomerization of C-peptide involves yet different and additional... |
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Intracellular signaling by C-peptide. Hills, C.E. and Brunskill, N.J.
Exp. Diabetes Res. , 635158, (2008)
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C-Peptide: A new mediator of atherosclerosis in diabetes. Vasic, D., and Walcher, D.
Mediators Inflamm. , 858692, (2012)
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The conformational protential of porcine proinsulin C-peptide. Vogt HP, Wollmer A, et al.
Hoppe. Seylers. Z. Physiol. Chem. 357 , 107-116, (1971)
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Proinsulin C-peptide prevents type-1 diabetes-induced decrease of renal Na+-K+-ATPase α1-subunit in rats. Nordquist L, Shimada K, et al.
Diabetes Metab. 26 , 193-199, (2010)
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