L-正亮氨酸
L-正亮氨酸结构式
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常用名 | L-正亮氨酸 | 英文名 | L-Norleucine |
|---|---|---|---|---|
| CAS号 | 327-57-1 | 分子量 | 131.173 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 234.0±23.0 °C at 760 mmHg | |
| 分子式 | C6H13NO2 | 熔点 | 300ºC | |
| MSDS | 中文版 美版 | 闪点 | 95.3±22.6 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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L-selenomethionine reduces platinum(IV) anticancer model compounds at strikingly faster rates than L-methionine.
Dalton Trans. 43(41) , 15328-36, (2014) L-Selenomethionine (SeMet), the predominant form of selenium acquired from the diet by humans, has been used as a supplement, and exhibit some important functions like cancer prevention and antioxidative defense. Its interactions with Pt(II) anticancer drugs ... |
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Leucine and alpha-ketoisocaproic acid, but not norleucine, stimulate skeletal muscle protein synthesis in neonatal pigs.
J. Nutr. 140(8) , 1418-24, (2010) The branched-chain amino acid, leucine, acts as a nutrient signal to stimulate protein synthesis in skeletal muscle of young pigs. However, the chemical structure responsible for this effect has not been identified. We have shown that the other branched-chain... |
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Changes in Serum Amino Acids in Migraine Patients without and with Aura and their Possible Usefulness in the Study of Migraine Pathogenesis.
CNS Neurol. Disord. Drug Targets 14(3) , 345-9, (2015) Results of several studies suggest that serum amino acids monitoring in migraine might be useful as an objective measurement of the disease status.The aim of the present work was to analyze the profile of aliphatic and aromatic amino acids in blood serum of m... |
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Optimization and validation of a chiral GC-MS method for the determination of free D-amino acids ratio in human urine: application to a gestational diabetes mellitus study.
J. Pharm. Biomed. Anal. 107 , 480-7, (2015) Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance with onset or first recognition during pregnancy. It is affecting approximately up to 14% of all pregnancies with an increasing tendency. GDM has been related to relevant short-term and lon... |
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Impact of Precursors Creatine, Creatinine, and Glucose on the Formation of Heterocyclic Aromatic Amines in Grilled Patties of Various Animal Species.
J. Food Sci. 80 , C2430-9, (2015) The impact of precursors such as creatine, creatinine, and glucose on the formation of mutagenic/carcinogenic heterocyclic amines (HAs) were studied in patties of 9 different animal species equally heat treated with a double-plate contact grill. All grilled p... |
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Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome.
Anal. Chem. 81(10) , 3919-32, (2009) We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass s... |
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Influence of Amino Acid Compositions and Peptide Profiles on Antioxidant Capacities of Two Protein Hydrolysates from Skipjack Tuna (Katsuwonus pelamis) Dark Muscle.
Mar. Drugs 13 , 2580-601, (2015) Influence of amino acid compositions and peptide profiles on antioxidant capacities of two protein hydrolysates from skipjack tuna (Katsuwonus pelamis) dark muscle was investigated. Dark muscles from skipjack tuna were hydrolyzed using five separate proteases... |
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L-leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst.
Appl. Microbiol. Biotechnol. 97(6) , 2467-72, (2013) L-Leucine 5-hydroxylase (LdoA) previously found in Nostoc punctiforme PCC 73102 is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase. LdoA catalyzed regio- and stereoselective hydroxylation of L-leucine and L-norleucine into (2S,4S)-5-hydroxyleucin... |
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The specificity and kinetic mechanism of branched-chain amino acid aminotransferase from Escherichia coli studied with a new improved coupled assay procedure and the enzyme's potential for biocatalysis.
FEBS J. 281(1) , 391-400, (2014) Branched-chain amino acid aminotransferase (BCAT) plays a key role in the biosynthesis of hydrophobic amino acids (such as leucine, isoleucine and valine), and its substrate spectrum has not been fully explored or exploited owing to the inescapable restrictio... |
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Inhibition of tissue transglutaminase 2 attenuates contractility of pregnant human myometrium.
Biol. Reprod. 84(4) , 646-53, (2011) Premature delivery remains a serious risk factor in pregnancy, with currently licensed tocolytics unable to offer significant improvement in neonatal outcome. Further understanding of the regulators of uterine contractility is required to enable the developme... |