2-氨基-1-丁醇
2-氨基-1-丁醇结构式
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常用名 | 2-氨基-1-丁醇 | 英文名 | 2-Amino-1-butanol |
|---|---|---|---|---|
| CAS号 | 96-20-8 | 分子量 | 89.136 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 177.2±13.0 °C at 760 mmHg | |
| 分子式 | C4H11NO | 熔点 | -2ºC | |
| MSDS | 中文版 美版 | 闪点 | 82.2±0.0 °C | |
| 符号 |
GHS05, GHS07, GHS09 |
信号词 | Danger |
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Universal spectropolarimeter based on overtone circular dichroism measurements in the near-infrared region.
Anal. Chem. 66(21) , 3639-43, (1994) A novel and highly sensitive circular dichroism spectropolarimeter for the near-infrared region has been developed. In this instrument, a solid state titanium-sapphire laser that can be spectrally tuned from 670 to 1030 nm was used as the light source. The la... |
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Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.
Biochemistry 41(37) , 11161-70, (2002) Cystic fibrosis commonly occurs as a consequence of the DeltaF508 mutation in the first nucleotide binding fold domain (NBF-1) of CFTR. The mutation causes retention of the mutant CFTR molecule in the endoplasmic reticulum, and this aberrant trafficking event... |
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Comparison of the cellular and biochemical properties of Plasmodium falciparum choline and ethanolamine kinases.
Biochem. J. 425(1) , 149-58, (2010) The proliferation of the malaria-causing parasite Plasmodium falciparum within the erythrocyte is concomitant with massive phosphatidylcholine and phosphatidylethanolamine biosynthesis. Based on pharmacological and genetic data, de novo biosynthesis pathways ... |
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Several lines of evidence demonstrating that Plasmodium falciparum, a parasitic organism, has distinct enzymes for the phosphorylation of choline and ethanolamine.
FEBS Lett. 202 , 217, (1986) In Plasmodium falciparum-infected erythrocyte homogenates, the specific activity of ethanolamine kinase (7.6 +/- 1.4 nmol phosphoethanolamine/10(7) infected cells per h) was higher than choline kinase specific activity (1.9 +/- 0.2 nmol phosphocholine/10(7) i... |
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Chronic Cadmium Exposure Lead to Inhibition of Serum and Hepatic Alkaline Phosphatase Activity in Wistar Rats.
J. Biochem. Mol. Toxicol. 29 , 587-94, (2016) Alkaline phosphatase (ALP) activity in the serum and liver from rats administered with cadmium (Cd) in drinking water was studied. After metal administration, Cd showed a time-dependent accumulation in the liver, meanwhile metallothionein had a maximum increa... |
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Determination of optical purity by high-performance liquid chromatography of compounds of pharmaceutical interest.
Il Farmaco 43(11) , 357-63, (1988)
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Chiral 2-amino-1-butanol xanthone derivatives as potential antiarrhythmic and hypotensive agents.
Acta Pol. Pharm. 56(1) , 87-90, (1999)
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The use of the Box-Behnken experimental design in the optimisation and robustness testing of a capillary electrophoresis method for the analysis of ethambutol hydrochloride in a pharmaceutical formulation.
J. Pharm. Biomed. Anal. 27(6) , 995-1007, (2002) Box-Behnken experimental designs do not appear to be extensively used in optimisation of analytical methods using capillary electrophoresis (CE). This paper describes the use of the Box-Behnken experimental design to optimise the factors affecting the separat... |
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Phospholipid metabolism as a new target for malaria chemotherapy. Mechanism of action of D-2-amino-1-butanol.
Biochem. Pharmacol. 33(17) , 2761-70, (1984) A number of choline and ethanolamine analogs were evaluated as inhibitors of P. falciparum growth in vitro. 1-Aziridineethanol, DL-2-amino-1,3-propranediol and D- or L-2-amino-1-butanol were the most efficient inhibitors of parasite multiplication, with an IC... |
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Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration.
Eur. J. Med. Chem. 48 , 45-56, (2012) The synthesis of 47 structurally diverse compounds incorporating the (R)-2-amino-1-butanol motif has been realized. Ten of these compounds were found to exhibit in vitro specific activity against Mycobacterium tuberculosis H37Rv in a MIC range of 0.65 μM-14.0... |