亚油酸胆固醇酯
亚油酸胆固醇酯结构式
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常用名 | 亚油酸胆固醇酯 | 英文名 | CHOLESTERYL LINOLEATE |
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| CAS号 | 604-33-1 | 分子量 | 649.084 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 677.3±44.0 °C at 760 mmHg | |
| 分子式 | C45H76O2 | 熔点 | 42ºC | |
| MSDS | 中文版 美版 | 闪点 | 364.0±16.0 °C |
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Autophagy facilitates secretion and protects against degeneration of the Harderian gland.
Autophagy 11(2) , 298-313, (2015) The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid droplets, while type B cells produce dark granules of multilamellar bodies. The process of autophagy is co... |
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A rapid and precise method for quantification of fatty acids in human serum cholesteryl esters by liquid chromatography and tandem mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 960 , 222-9, (2014) We described a rapid and precise method for simultaneous quantification of eleven fatty acids in human serum cholesteryl esters (CEFAs) by liquid chromatography and tandem mass spectrometry (LC-MS/MS). After extraction of serum lipids with isopropanol, CEFAs ... |
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Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.
Arterioscler. Thromb. Vasc. Biol. 22(4) , 581-6, (2002) Oxidation products of cholesteryl esters have been shown to be present in oxidized low density lipoprotein and in atherosclerotic lesions. Monocyte adhesion to the endothelium is an initiating crucial event in atherogenesis. Here, we show that in vitro oxidiz... |
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Assessment of alkaline cholesterol oxidase purified from Rhodococcus sp. PKPD-CL for its halo tolerance, detergent and organic solvent stability.
Protein Expr. Purif. 116 , 30-41, (2015) The novel bacterium, Rhodococcus sp. PKPD-CL was isolated and identified from the 'Chilika Lake' located at Odisha state of India, which is a largest brackish water habitat in Asia. Rhodococcus sp. PKPD-CL produces extracellular halo tolerant, detergent and o... |
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Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. Reconstitution of a biologically active lipoprotein particle.
J. Biol. Chem. 253 , 4093-101, (1978)
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Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid.
J. Immunol. 181 , 4177-4187, (2008) Mucosal surfaces provide first-line defense against microbial invasion through their complex secretions. The antimicrobial activities of proteins in these secretions have been well delineated, but the contributions of lipids to mucosal defense have not been d... |
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Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake.
Int. J. Nanomedicine 5 , 679-86, (2010) Use of lipid nanoemulsions as carriers of drugs for therapeutic or diagnostic purposes has been increasingly studied. Here, it was tested whether modifications of core particle constitution could affect the characteristics and biologic properties of lipid nan... |
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LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat.
J. Lipid Res. 50 , S434-S439, (2009) This review focuses on the relationships among dietary fat type, plasma and liver lipid, and lipoprotein metabolism and atherosclerosis. Dietary polyunsaturated fatty acids are beneficial for the prevention of coronary artery atherosclerosis. By contrast, die... |
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The regional ratio of cholesteryl palmitate to cholesteryl oleate measured by ToF-SIMS as a key parameter of atherosclerosis.
Atherosclerosis 226(2) , 378-84, (2013) Changes in cholesterol ester (CE) content regulate the progression of atherosclerosis. However, the spatial dynamics of CE subsets and their quantitative changes during lesion progression are not well understood due to a lack of appropriate imaging techniques... |
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Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
Arterioscler. Thromb. Vasc. Biol. 31(5) , 1108-15, (2011) Pyripyropene A (PPPA) of fungal origin is the first compound that has been found to strongly and selectively inhibit acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) isozyme activity in vitro. The purpose of the present study was to investigate in vivo e... |