S-苯汞基酸
S-苯汞基酸结构式
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常用名 | S-苯汞基酸 | 英文名 | S-Phenylmercapturic Acid |
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| CAS号 | 4775-80-8 | 分子量 | 211.28100 | |
| 密度 | N/A | 沸点 | 494.5ºC at 760 mmHg | |
| 分子式 | C10H13NO2S | 熔点 | 110-112ºC | |
| MSDS | 中文版 美版 | 闪点 | 252.9ºC |
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Influence of genetic polymorphism on t,t-MA/S-PMA ratio in 301 benzene exposed subjects.
Toxicol. Lett. 231(2) , 205-12, (2014) This study investigated the effect of polymorphic genes GSTT1, GSTM1, GSTA1, EHPX1, NQO1, CYP2E1, CYP1A and MPO on the urinary concentrations and ratio (R) of the benzene metabolites trans,trans-muconic acid (t,t-MA) and S-phenyl mercapturic acid (S-PMA) in 3... |
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Metabolic polymorphisms and biomarkers of effect in the biomonitoring of occupational exposure to low-levels of benzene: state of the art.
Toxicol. Lett. 231(2) , 194-204, (2014) Current levels of occupational exposure to benzene, a genotoxic human carcinogen, in Western countries are reduced by two-three orders of magnitude (from ppm to ppb) as compared to the past. However, as benzene toxicity is strongly dependent on biotransformat... |
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Urinary trans, trans-muconic acid and S-phenylmercapturic acid are indicative of exposure to urban benzene pollution during childhood.
Sci. Total Environ. 435-436 , 115-23, (2012) The aims of the study were to evaluate the feasibility of urinary trans, trans-muconic acid (u-t,t-MA) and urinary S-phenylmercapturic acid (u-SPMA) as markers of exposure to urban benzene pollution for biomonitoring studies performed on children and to inves... |
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Association between environmental exposure to benzene and oxidative damage to nucleic acids in children.
Med. Lav. 103(5) , 324-37, (2012) To evaluate the association between environmental exposure to benzene and oxidative damage to nucleic acids in children, also considering the role of Environmental Tobacco Smoke (ETS).396 children living in central Italy were recruited in districts with diffe... |
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Biological monitoring of low-level exposure to benzene.
Med. Lav. 103(5) , 338-46, (2012) Conflicting opinions exist about the reliability of biomarkers of low-level exposure to benzene. We compared the ability of the urinary excretion of trans,trans-muconic acid (t,t-MA), s-phenilmercapturic acid (s-PAMA) and urinary benzene (U-Benz) to detect lo... |
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Methodological issues in the biological monitoring of urinary benzene and S-phenylmercapturic acid at low exposure levels.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(27) , 2534-40, (2010) Biological monitoring of low level exposure to pollutants is a very challenging analytical activity, and the quality of results is difficult to assess, especially when a certified reference material is unavailable. The aim of this work was to evaluate the rel... |
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Comparison of hydrolysis and HPLC/MS/MS procedure with ELISA assay for the determination of S-phenylmercapturic acid as a biomarker of benzene exposure in human urine.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(27) , 2529-33, (2010) The present study compared three methods for the determination of S-phenylmercapturic acid (S-PMA), a metabolite of benzene, in human urine: a HPLC/MS/MS technique with two different sample treatments (strong and partial hydrolysis) and a commercial assay bas... |
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Benzene exposure during tunnelling--using biological monitoring to assess control measures and working practice.
Ann. Occup. Hyg. 55(3) , 248-52, (2011) This paper reports the assessment of worker exposure to high levels of benzene (up to 18 p.p.m. 8 h time weighted average, weekly average) during tunnelling on a contaminated land site (former gas works). Although respiratory and personal protection was used,... |
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Defining the contribution of non-benzene sources of benzene metabolites in urine: implications for biomonitoring and risk assessment.
Chem. Biol. Interact. 184(1-2) , 299-301, (2010)
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Trans, trans-muconic acid as a biomarker of occupational exposure to high-level benzene in China.
J. Occup. Environ. Med. 53(10) , 1194-8, (2011) The work aimed to study the potential correlation between the high-level benzene exposure and its urinary metabolites S-phenylmercapturic acid (SPMA) and trans, trans-muconic acid (t,t-MA) in Chinese shoe-making workers.Individual benzene-exposed levels were ... |