1,2,3,4-四氢喹啉
1,2,3,4-四氢喹啉结构式
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常用名 | 1,2,3,4-四氢喹啉 | 英文名 | 1,2,3,4-Tetrahydroquinoline |
|---|---|---|---|---|
| CAS号 | 635-46-1 | 分子量 | 133.190 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 250.8±10.0 °C at 760 mmHg | |
| 分子式 | C9H11N | 熔点 | 9-14 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 100.6±0.0 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Discovery of thienoquinolone derivatives as selective and ATP non-competitive CDK5/p25 inhibitors by structure-based virtual screening.
Bioorg. Med. Chem. 22(22) , 6409-21, (2014) Calpain mediated cleavage of CDK5 natural precursor p35 causes a stable complex formation of CDK5/p25, which leads to hyperphosphorylation of tau. Thus inhibition of this complex is a viable target for numerous acute and chronic neurodegenerative diseases inv... |
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Pharmacokinetic plasma behaviors of intravenous and oral bioavailability of thymoquinone in a rabbit model.
Eur. J. Drug Metab. Pharmacokinet. 40 , 319-23, (2015) Thymoquinone (THQ), the active constituent of Nigella sativa seeds, has demonstrated some potential pharmacological activities. The present study was designed to investigate the pharmacokinetic behavior of THQ following intravenous (IV) and oral (PO) administ... |
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