叔丁基过氧化氢
一般危化品
叔丁基过氧化氢结构式
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常用名 | 叔丁基过氧化氢 | 英文名 | tert-Butyl Hydroperoxide |
|---|---|---|---|---|
| CAS号 | 75-91-2 | 分子量 | 90.121 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 120.4±9.0 °C at 760 mmHg | |
| 分子式 | C4H10O2 | 熔点 | -2.8 °C | |
| MSDS | 中文版 美版 | 闪点 | 35.0±0.0 °C | |
| 符号 |
GHS02, GHS05, GHS06, GHS08, GHS09 |
信号词 | Danger |
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bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway.
J. Cell. Mol. Med. 19(3) , 595-607, (2015) Extensive research focused on finding effective strategies to prevent or improve recovery from myocardial ischaemia/reperfusion (I/R) injury. Basic fibroblast growth factor (bFGF) has been shown to have therapeutic potential in some heart disorders, including... |
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Synthesis of PS/PO-chimeric oligonucleotides using mixed oxathiaphospholane and phosphoramidite chemistry.
Org. Biomol. Chem. 13(1) , 269-76, (2014) Chimeric oligonucleotides containing phosphodiester and phosphorothioate linkages have been obtained using the solid phase synthesis. The oligonucleotide parts possessing natural internucleotide phosphate bonds were assembled using commercially available nucl... |
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Biocompatibility evaluation of porous ceria foams for orthopedic tissue engineering.
J. Biomed. Mater. Res. A 103(1) , 8-15, (2014) Ceria ceramics have the unique ability to protect cells from free radical-induced damage, making them materials of interest for biomedical applications. To expand upon the understanding of the potential of ceria as a biomaterial, porous ceria, fabricated via ... |
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Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.
Br. J. Nutr. 113(5) , 770-82, (2015) Type 1 diabetes (T1D), an autoimmune inflammatory disorder, develops as a consequence of pancreatic β-cell destruction and results in hyperglycaemia. Since current T1D therapy mainly involves insulin replacement, the aim of the present study was to evaluate t... |
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Resveratrol Attenuates Oxidative Stress and Extends Life Span in the Annual Fish Nothobranchius guentheri.
Rejuvenation Res. 18 , 225-33, (2015) Resveratrol is a natural polyphenol derived mainly from the skin of grapes and from red wine. Resveratrol prolongs life span in several invertebrates, but this function is not found in mice. Our recently published paper demonstrated that resveratrol prolonged... |
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Effect of individual Fc methionine oxidation on FcRn binding: Met252 oxidation impairs FcRn binding more profoundly than Met428 oxidation.
J. Pharm. Sci. 104(2) , 368-77, (2015) The long serum half-lives of mAbs are conferred by pH-dependent binding of IgG-Fc to the neonatal Fc receptor (FcRn). The Fc region of human IgG1 has three conserved methionine residues, Met252, Met358, and Met428. Recent studies showed oxidation of these Met... |
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High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity.
Toxicol. In Vitro 29 , 1916-31, (2015) Testing hepatotoxicity is a crucial step in the development and toxicological assessment of drugs and chemicals. Bio-activation can lead to the formation of metabolites which may present toxicity for the organism. Classical cytotoxic tests are not always appr... |
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Mechanism of Dose-Dependent Regulation of UBE1L by Polyphenols in Human Bronchial Epithelial Cells.
J. Cell. Biochem. 116 , 1553-62, (2015) Ubiquitin activating enzyme E1-like (UBE1L) is the activating enzyme for ISG15ylation (ISG15, interferon stimulated gene 15). UBE1L is thought to be a candidate tumor suppressor gene and has positive activity against stress responses such as viral infections.... |
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Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.
Neurotox. Res. 28 , 32-42, (2015) Deposition of amyloid-β (Aβ) peptides into specific encephalic structures has been pointed as an important event related to Alzheimer's disease pathogenesis and associated with activation of glial cells, neuroinflammation, oxidative responses, and cognitive d... |
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Fungal metabolite nigerloxin ameliorates diabetic nephropathy and gentamicin-induced renal oxidative stress in experimental rats.
Naunyn Schmiedebergs Arch. Pharmacol. 387(9) , 849-59, (2014) Elevated polyol pathway enzyme activities and oxidative stress play an important role in the development and progression of diabetic nephropathy. Here, we investigated the beneficial influence of nigerloxin, a fungal metabolite and a potent aldose reductase i... |