5-溴-1H-吲哚-1-甲酸叔丁酯
5-溴-1H-吲哚-1-甲酸叔丁酯结构式
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常用名 | 5-溴-1H-吲哚-1-甲酸叔丁酯 | 英文名 | TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE |
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| CAS号 | 182344-70-3 | 分子量 | 296.16000 | |
| 密度 | 1.37g/cm3 | 沸点 | 367.9ºC at 760mmHg | |
| 分子式 | C13H14BrNO2 | 熔点 | 56-57ºC(lit.) | |
| MSDS | 中文版 | 闪点 | 176.3ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.
ChemMedChem 4 , 261, (2009) The lead compound 5-bromoindolyl-3-acetohydroxamic acid (10) was recently identified as a potent inhibitor of bacterial peptide deformylases (PDFs). The synthesis and associated activities of new variants were investigated at position 5 to optimize the fit at... |
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Synthesis of heterocyclic allenes via palladium-catalyzed hydride-transfer reaction of propargylic amines.
J. Org. Chem. 70(6) , 2357-60, (2005) [reaction: see text] Propargylic diisopropylamines containing heterocycles, which were prepared readily from heterocyclic bromides and propargyldiisopropylamine by the Sonogashira coupling reaction, underwent the allene transformation reaction in the presence... |
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