磺胺二甲异嘧啶钠
磺胺二甲异嘧啶钠结构式
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常用名 | 磺胺二甲异嘧啶钠 | 英文名 | Sulfamethazine sodium salt |
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| CAS号 | 1981-58-4 | 分子量 | 300.312 | |
| 密度 | 1.392g/cm3 | 沸点 | 526.2ºC at 760mmHg | |
| 分子式 | C12H13N4NaO2S | 熔点 | 176ºC | |
| MSDS | 中文版 美版 | 闪点 | 272.1ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.
Sci. Total Environ. 511 , 153-60, (2015) The development, characterisation and application of a new analytical method for multi-residue PPCP determination in the freshwater amphipod, Gammarus pulex are presented. Analysis was performed using pulverised liquid extraction (PuLE), solid phase extractio... |
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic Acids Res. 39 , D1035-41., (2011) DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, pharmacology, pharmacokinetics, metabolism and pharmaceutic... |
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Depletion kinetics of 14C-sulfamethazine [4-amino-N-(4, 6-dimethyl-2-pyrimidinyl)benzene[U-14C]sulfonamide] metabolism in swine.
Drug Metab. Dispos. 14 , 161, (1986) Swine weighing 60-70 kg were orally administered 14C-sulfamethazine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzene[U-14C]sulfonamide] at 12-hr intervals for 7 days (165 mg/dose; 0.126-5.04 mCi/mmol). The animals were sacrificed at 8 hr or 2, 5, or 10 days aft... |
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Relationship of sulfamethazine disposition kinetics to acetylator phenotype in man. A preliminary study.
J. Clin. Pharmacol. 16 , 338-344, (1976) The relationship between sulfamethazine disposition kinetics and acetylation phenotype was studied in man. Sulfamethazine pharmacokinetic parameters were determined after the administration of the drug as an oral suspension. When the half-life, acetylation ra... |
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Development of a sensitive monoclonal antibody-based ELISA for the detection of sulfamethazine in cow milk, honey, and swine urine.
Hybridoma 29 , 403-407, (2010) A specific monoclonal antibody (MAb) against sulfamethazine was produced with hybridoma technology. This assay shows very high sensitivity with IC50 of 0.4 ng/mL and LOD of 0.05 ng/mL when it was run in 0.02 mol/L PBS (pH 7.5). This MAb has shown high specifi... |