5-羟基色氨酸
5-羟基色氨酸结构式
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常用名 | 5-羟基色氨酸 | 英文名 | L-5-Hydroxytryptophan |
|---|---|---|---|---|
| CAS号 | 4350-09-8 | 分子量 | 220.22 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 520.6±50.0 °C at 760 mmHg | |
| 分子式 | C11H12N2O3 | 熔点 | 270 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 268.7±30.1 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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The murine serotonin syndrome - evaluation of responses to 5-HT-enhancing drugs in NMRI mice.
Behav. Brain Res. 277 , 204-10, (2014) In humans, the ingestion of the combination of two or more serotonin (5-HT)-enhancing drugs but also of a single drug in overdose can induce serious adverse effects, which are characteristics of the serotonin syndrome (SS). In mice, acute administration of di... |
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Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign).
J. Nat. Prod. 72 , 44-52, (2009) This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and converted to prenylated derivatives. The structures of the e... |
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The effect of low dose rate on metabolomic response to radiation in mice.
Radiat. Environ. Biophys. 53(4) , 645-57, (2014) Metabolomics has been shown to have utility in assessing responses to exposure by ionizing radiation (IR) in easily accessible biofluids such as urine. Most studies to date from our laboratory and others have employed γ-irradiation at relatively high dose rat... |
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Antidepressant and anti-anxiety like effects of 4i (N-(3-chloro-2-methylphenyl) quinoxalin-2-carboxamide), a novel 5-HT3 receptor antagonist in acute and chronic neurobehavioral rodent models.
Eur. J. Pharmacol. 735 , 59-67, (2014) Depression and anxiety are the most debilitating mood disorders with poor therapeutic recovery rates. In the last decades, 5-HT3 receptor antagonists have been identified as potential agents for mood disorders. The current investigation focuses on evaluating ... |
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Involvement of norepinephrine and serotonin system in antidepressant-like effects of oleoylethanolamide in the mice models of behavior despair.
Neurosci. Lett. 593 , 24-8, (2015) Oleoylethanolamide (OEA) is an endocannabinoid analogy that belongs to a family of endogenous acylethanolamides. Increasing evidence suggests that OEA may act as an endogenous neuroprotective factor and participate in the control of mental disorder-related be... |