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2-甲胺乙醇

2-甲胺乙醇结构式
2-甲胺乙醇结构式
品牌特惠专场
常用名 2-甲胺乙醇 英文名 2-Methylaminoethanol
CAS号 109-83-1 分子量 75.110
密度 0.9±0.1 g/cm3 沸点 159.9±13.0 °C at 760 mmHg
分子式 C3H9NO 熔点 -3 °C
MSDS 中文版 美版 闪点 73.9±0.0 °C
符号 GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
信号词 Danger

Enzymatic properties and substrate specificity of a bacterial phosphatidylcholine synthase.

FEBS J. 281(15) , 3523-41, (2014)

Phosphatidylcholine (PC) is a rare membrane lipid in bacteria, but is crucial for virulence of the plant pathogen Agrobacterium tumefaciens and various other pathogens. Agrobacterium tumefaciens uses two independent PC biosynthesis pathways. One is dependent ...

Acute toxicity and primary irritancy of alkylalkanolamines.

Vet. Hum. Toxicol. 38(6) , 422-6, (1996)

The acute handling hazards of several alkylalkanolamines were determined by investigating their potential acute toxicity and primary irritancy. Materials studied were N-methylethanolamine (MEA), N, N, -dimethylethanolamine (DMEA), N, N, -dimethylisopropanolam...

Recovery of choline oxidase activity by in vitro recombination of individual segments.

Appl. Microbiol. Biotechnol. 81(2) , 275-82, (2008)

Initial attempts to express a choline oxidase from Arthrobacter pascens (APChO-syn) in Escherichia coli starting from a synthetic gene only led to inactive protein. However, activity was regained by the systematic exchange of individual segments of the gene w...

3-D-QSAR and docking studies on the neuronal choline transporter.

Bioorg. Med. Chem. Lett. 20 , 4870-7, (2010)

The high affinity neuronal choline transporter (CHT1) is responsible for the uptake of choline into the pre-synaptic terminal of cholinergic neurons. Considering our past experience with modeling the blood-brain barrier choline transporter (BBBCHT) as drug de...

Collision-induced dissociation of aminophospholipids (PE, MMPE, DMPE, PS): an apparently known fragmentation process revisited.

Anal. Bioanal. Chem 407 , 5079-89, (2015)

A new type of low-mass substituted 4-oxazolin product ions of [M + H](+) precursor ions of aminophospholipids (glycerophosphatidylethanolamine, glycerophosphatidyl-N-methylethanolamine, glycerophosphatidyl-N,N-dimethylethanolamine, glycerophosphatidylserine) ...

Enzymatic chemoselective synthesis of secondary-amide surfactant from N-methylethanol amine.

J. Biosci. Bioeng. 100(6) , 662-6, (2005)

Efficient selective synthesis of the secondary amide surfactant N-methyl lauroylethanolamide from methyl laurate and N-methylethanol amine by carrier-fixed Chirazyme L-2 (Candida antarctica) using a kinetic strategy has been demonstrated. When different solve...

N-methylethanolamine attenuates cardiac fibrosis and improves diastolic function: inhibition of phospholipase D as a possible mechanism.

Eur. Heart J. 25(14) , 1221-9, (2004)

Ventricular fibrosis is promoted by many effectors that chronically activate phospholipase D (PLD), and induces cardiac dysfunction and heart failure in cardiovascular diseases. Since ethanolamine is a product of PLD, we hypothesised that an administration of...

Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.

Biochemistry 41(37) , 11161-70, (2002)

Cystic fibrosis commonly occurs as a consequence of the DeltaF508 mutation in the first nucleotide binding fold domain (NBF-1) of CFTR. The mutation causes retention of the mutant CFTR molecule in the endoplasmic reticulum, and this aberrant trafficking event...

Comparative inhalation teratogenicity of four glycol ether solvents and an amino derivative in rats.

Environ. Health Perspect. 57 , 261-71, (1984)

Previous research demonstrated the inhalation teratogenicity of the solvent 2-ethoxyethanol in rats and rabbits. As this is one of a class of widely used industrial solvents, we investigated the teratogenicity of five structurally related compounds. Each chem...

Increased levels of methylated intermediates of phosphatidylcholine lead to enhanced phospholipase D activity.

Neurochem. Res. 23(8) , 1099-105, (1998)

Previous work from this laboratory and others has shown that neurotransmitters can activate phospholipase D. Unlike the phospholipase C that specifically hydrolyzes inositol-containing phospholipids, phospholipase D in neuronal tissue specifically hydrolyzes ...