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3-碘-4甲基苯甲酸

3-碘-4甲基苯甲酸结构式
3-碘-4甲基苯甲酸结构式
品牌特惠专场
常用名 3-碘-4甲基苯甲酸 英文名 3-Iodo-4-methylbenzoic acid
CAS号 82998-57-0 分子量 262.044
密度 1.9±0.1 g/cm3 沸点 355.2±30.0 °C at 760 mmHg
分子式 C8H7IO2 熔点 210-212 °C(lit.)
MSDS 中文版 美版 闪点 168.6±24.6 °C
符号 GHS07
GHS07
信号词 Warning

A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB).

Bioconjug. Chem. 12(3) , 428-38, (2001)

The objective of this study was to develop an acylation agent for the radioiodination of monoclonal antibodies that would maximize retention of the label in tumor cells following receptor- or antigen-mediated internalization. The strategy taken was to add a p...

Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides.

Nat. Protoc. 2(2) , 282-6, (2007)

This protocol describes a detailed procedure for the synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate ([*I]SGMIB), an agent useful in the radio-iodination of proteins, including monoclonal Abs, and peptides that undergo internalization after r...