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盐酸醋丁洛尔

盐酸醋丁洛尔结构式
盐酸醋丁洛尔结构式
品牌特惠专场
常用名 盐酸醋丁洛尔 英文名 Acebutolol HCl
CAS号 34381-68-5 分子量 372.887
密度 N/A 沸点 564.1ºC at 760 mmHg
分子式 C18H29ClN2O4 熔点 141-1430C
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Solubility-pH profiles of some acidic, basic and amphoteric drugs.

Eur. J. Pharm. Sci. 48(1-2) , 291-300, (2013)

The solubility vs. pH profiles of five ionizable drugs of different nature (a monoprotic acid, a monoprotic base, a diprotic base and two amphoteric compounds showing a zwitterionic species each one) have been determined through two different methodologies: t...

Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry.

Biomed. Chromatogr. 22(7) , 702-11, (2008)

A detailed procedure for the analysis of four beta-blockers, acebutolol, labetalol, metoprolol and propranolol, in human plasma by high-performance liquid chromatography (LC)-tandem mass spectrometry (MS-MS) using an MSpak GF column, which enables direct inje...

First record of Prorocentrum lima (Dinophyceae) inside harbor areas and along the Abruzzo region coast, W Adriatic.

Mar. Pollut. Bull. 58(4) , 596-600, (2009)

Prorocentrum lima (Ehrenberg) Dodge has been found for the first time during the summer of 2007 inside Ortona harbor and along the coast of the Abruzzo region, a slightly eutrophic area influenced by runoff from a nearby river. The investigations were conduct...

Follow-up with exercise test of effort-induced ventricular arrhythmias linked to ryanodine receptor type 2 gene mutations.

Am. J. Cardiol. 109(7) , 1015-9, (2012)

The aim of this study was to assess exercise test results and efficacy of therapy with a β blocker (acebutolol) in ryanodine receptor type 2 (RyR2) mutation carriers with documented ventricular arrhythmias (VAs) and long-term follow-up. Twenty RyR2 mutation c...

Active components of frequently used β-blockers from the aspect of computational study.

J. Mol. Model. 18(9) , 4491-501, (2012)

The aim of this study is to investigate the active components of representative drugs for blood pressure regulation by applying quantum mechanical computer codes and comparison of the same for the sake of obtaining knowledge about the properties associated wi...

1H and 13C NMR characteristics of β-blockers.

Magn. Reson. Chem. 49(5) , 284-90, (2011)

The β-blockers are important drugs and decades of clinical experience proved their high medical status. However, to the best of our knowledge, there is no complete assignment of (1)H and (13)C NMR resonances of popular representatives: acebutolol, alpenolol, ...

Evaluation of the impact on entomocoenosis of active agents allowed in organic olive farming against Bactrocera oleae (Gmelin, 1790).

J. Environ. Sci. Health B 42(7) , 783-8, (2007)

Several attempts for evaluating environmental impact of active agents allowed in organic olive farming against Bactrocera oleae have been made, but very few studies were performed contemporaneously on more than one of them. Insects were chosen as indicators b...

Stability of chosen beta-adrenolytic drugs of different polarity in basic environment.

J. AOAC Int. 91(2) , 322-31, (2008)

The stability of atenolol, acebutolol, and propranolol was investigated in sodium hydroxide solutions at concentrations of 0.1, 0.3, 0.5, and 1 M at 3 temperatures ranging from 37 to 95 degrees C. The degradation processes that occurred in drugs under investi...

Stability of atenolol, acebutolol and propranolol in acidic environment depending on its diversified polarity.

Pharm. Dev. Technol. 11(4) , 409-16, (2006)

The main objective of this research was to investigate the relationship between the polarity of atenolol, acebutolol, and propranolol described by logP and kinetic and thermodynamic parameters characterizing their degradation process in acidic solution. Hydro...

A severe case of Aeromonas veronii biovar sobria travellers' diarrhoea characterized by Vibrio parahaemolyticus co-isolation.

J. Med. Microbiol. 62(Pt 1) , 161-4, (2013)

We report a severe case of travellers' diarrhoea in a patient returning from Ecuador to Italy with the concomitant presence of Aeromonas veronii biovar sobria and Vibrio parahaemolyticus in their faeces. Based on diagnostic results, epidemiological informatio...