氨基甲酸甲酯
氨基甲酸甲酯结构式
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常用名 | 氨基甲酸甲酯 | 英文名 | Methyl carbamate |
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| CAS号 | 598-55-0 | 分子量 | 75.067 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 178.7±8.0 °C at 760 mmHg | |
| 分子式 | C2H5NO2 | 熔点 | 56-58 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 105.2±14.8 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Warning |
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The dissociation chemistry of ionized methyl carbamate and its isomers revisited: theory and experiment in concert.
Eur. J. Mass Spectrom. (Chichester, Eng.) 18(2) , 149-59, (2012) Early combined computational and experimental studies by J.K. Terlouw c.s. in Refs. 1-3 propose that low-energy methyl carbamate ions, NH(2)COOCH(3)(•+) (MC-1), rearrange into distonic ions NH(2)C(OH)OCH(2)(•+) and hydrogen-bridged radical cations [NH(2)C=O--... |
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Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, dibromoacetonitrile and 2-hydroxypropionitrile induce chromosome loss in Saccharomyces cerevisiae.
Mutat. Res. 270(2) , 151-66, (1992) Induction of mitotic chromosome loss could be demonstrated for the dialdehyde glyoxal, the diketones 2,3-butanedione and 2,3-hexanedione, ethyl and methyl carbamate, ethyl acrylate, dibromoacetonitrile, 2-hydroxypropionitrile and formaldehyde, but only when t... |
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Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics.
J. Med. Chem. 53 , 5281-5289, (2010) Niemann-Pick type C (NPC) disease is a lysosomal storage disorder characterized at the cellular level by abnormal accumulation of cholesterol and other lipids in lysosomal storage organelles. Lysosomal acid lipase (LAL) has been recently identified as a poten... |
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Equilibrium vs ground-state planarity of the CONH linkage.
J. Phys. Chem. A 111(13) , 2574-86, (2007) Planarity of the XC(=)NHY linkage has been investigated in unprecedented detail in a number of relatively simple compounds, including formamide (X = Y = H), acetamide (X = CH3, Y = H), urea (X = NH2, Y = H), carbamic acid (X = OH, Y = H), and methyl carbamate... |
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Analysis of Fungicide Sensitivity and Genetic Diversity among Colletotrichum Species in Sweet Persimmon.
Plant Pathol. J. 31 , 115-22, (2015) Anthracnose, caused by Colletotrichum gloeosporioides (C. gloeosporioides; Teleomorph: Glomerella cingulata), is the most destructive disease that affects sweet persimmon production worldwide. However, the biology, ecology, and genetic variations of C. gloeos... |
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Immunotoxicity of ethyl carbamate in female BALB/c mice: role of esterase and cytochrome P450.
Toxicol. Lett. 115(3) , 173-81, (2000) Ethyl carbamate, a potent carcinogen, has been characterized to be metabolized by cytochrome P450 (P450) and esterase. It has recently been demonstrated that P450 may activate ethyl carbamate to immunotoxic metabolites. To investigate the role of esterase in ... |
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A rapid route to aminocyclopropanes via carbamatoorganozinc carbenoids.
Angew. Chem. Int. Ed. Engl. 52(38) , 10060-3, (2013) Easy as 1,2,3: Reaction of methyl carbamate, triethyl orthoformate, and readily available alkenes provides a highly practical preparation of protected aminocyclopropanes. The reaction proceeds with preferential cis addition to alkenes, and cleavage of the met... |
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Symptoms of psychological distress and suicidal ideation among banana workers with a history of poisoning by organophosphate or n-methyl carbamate pesticides.
Occup. Environ. Med. 67(11) , 778-84, (2010) Neuropsychiatric disorders and increased suicide rates have been associated with exposure to cholinesterase inhibiting organophosphates. This study examined symptoms of psychological distress, including suicidal ideation, among banana workers in Costa Rica pr... |
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Application of liquid chromatography/thermospray mass spectrometry to studies on the formation of glutathione and cysteine conjugates from monomethylcarbamate metabolites of bambuterol.
Rapid Commun. Mass Spectrom. 3(10) , 360-3, (1989) Liquid chromatography/thermospray mass spectrometry (LC/TSP-MS) has been used to identify and study the rates of formation of S-(N-methylcarbamoyl)cysteine and S-(N-methylcarbamoyl)glutathione as products of the in vitro reaction of cysteine and glutathione, ... |
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Chronic neurologic sequelae to cholinesterase inhibition among agricultural pesticide applicators.
Arch. Environ. Health 50(6) , 440-4, (1995) To test the hypothesis that chronic neurologic sequelae are associated with cholinesterase depression short of frank organophosphate poisoning, we compared 45 male subjects who had a history of moderate cholinesterase inhibition with 90 male subjects who had ... |