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3-氟苯胺

一般危化品
3-氟苯胺结构式
3-氟苯胺结构式
常用名 3-氟苯胺 英文名 3-fluoroaniline
CAS号 372-19-0 分子量 111.117
密度 1.2±0.1 g/cm3 沸点 186.3±13.0 °C at 760 mmHg
分子式 C6H6FN 熔点 -2°C
MSDS 中文版 美版 闪点 77.2±0.0 °C
符号 GHS05 GHS07
GHS05, GHS07
信号词 Danger

cIEF for rapid pKa determination of small molecules: a proof of concept.

Eur. J. Pharm. Sci. 63 , 14-21, (2014)

A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap...

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)

Study on the regioselectivity and mechanism of the aromatic hydroxylation of monofluoroanilines.

Chem. Biol. Interact. 85(2-3) , 151-72, (1992)

The in vitro and in vivo metabolism of monofluoroanilines was investigated. Special attention was focused on the regioselectivity of the aromatic hydroxylation by cytochromes P-450 and the mechanism by which this reaction might proceed. The results clearly de...