十六烷二酸
十六烷二酸结构式
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常用名 | 十六烷二酸 | 英文名 | Hexadecanedioic acid |
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| CAS号 | 505-54-4 | 分子量 | 286.407 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 457.5±18.0 °C at 760 mmHg | |
| 分子式 | C16H30O4 | 熔点 | 120-123 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 244.6±17.7 °C |
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Feasibility of detecting prostate cancer by ultraperformance liquid chromatography-mass spectrometry serum metabolomics.
J. Proteome Res. 13(7) , 3444-54, (2014) Prostate cancer (PCa) is the second leading cause of cancer-related mortality in men. The prevalent diagnosis method is based on the serum prostate-specific antigen (PSA) screening test, which suffers from low specificity, overdiagnosis, and overtreatment. In... |
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Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the induction of peroxisomal beta-oxidation.
J. Lipid Res. 30(11) , 1711-8, (1989) Previous work in this laboratory indicated that sulfur-substituted fatty acid analogues, 1.10-bis(carboxymethylthio)decane and alkylthioacetic acid, both non-beta-oxidizable compounds, and the beta-oxidizable alkylthiopropionic acid (1) caused, to different e... |
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Subcellular localization of hexadecanedioic acid activation in human liver.
J. Lipid Res. 15(6) , 551-6, (1974) The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 micro mole/min/g wet wt of tissue, about 10% of that for palmitic acid. Hexadecan... |
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Alkyl and carboxylalkyl esters of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxic, and antitumor activity.
Eur. J. Med. Chem. 39(2) , 189-93, (2004) Esters of 4'-demethyl-4-deoxypodophyllotoxin (DDPT) with alkanoic acids and alkanedioic acids were prepared and tested for cytotoxic and antitumor activity. Among 19 esters, esters of propanoic acid, tetradecanedioic acid, 13-carboxyundecanoic acid, and hexad... |
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Cytochrome P450BM-3 (CYP102): regiospecificity of oxidation of omega-unsaturated fatty acids and mechanism-based inactivation.
Biochemistry 32(49) , 13732-41, (1993) Cytochrome P450BM-3 preferentially oxidized fatty acids with terminal double or triple bonds to the omega-2 hydroxylated fatty acids rather than, respectively, to the epoxide or diacid metabolites. The enzyme is inactivated during catalytic turnover of long, ... |
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Hexadecanedionic acid-sepharose 4B: A new tool for preparation of albumin-depleted plasma.
J. Proteome Res. 5(12) , 3453-8, (2006) Serum and plasma are the major sources of human material for clinical molecular diagnostics and drug discovery. However, due to the high abundance of some proteins, of which serum albumin (SA) is most prominent, lower-abundance proteins often remain undetecta... |
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Synthesis and bio-evaluation of a new fatty acid derivative for myocardial imaging.
Bioorg. Med. Chem. 16(17) , 7927-31, (2008) Development of a (99m)Tc-fatty acid analogue is of interest, as (99m)Tc is logistically advantageous over the cyclotron-produced (11)C and (123)I. Synthesis of a 16 carbon fatty acid derivative and its radiolabeling with the novel [(99m)TcN(PNP)](2+) core is ... |