克利溴铵
克利溴铵结构式
|
常用名 | 克利溴铵 | 英文名 | clidinium bromide |
|---|---|---|---|---|
| CAS号 | 3485-62-9 | 分子量 | 432.351 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C22H26BrNO3 | 熔点 | 240-241°C | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82).
J. Pharmacol. Exp. Ther. 256 , 689, (1991) The radioligand binding and functional properties of 10 muscarinic agonists for the M1 muscarinic receptors were characterized on the murine fibroblast B82 cells, which have been transfected with the m1 gene. All of the muscarinic agonists completely inhibite... |
|
|
Simultaneous spectrophotometric determination of chlordiazepoxide and clidinium using multivariate calibration techniques.
Drug Test. Anal. 2(9) , 430-5, (2010) Three multivariate modelling approaches including partial least squares regression (PLS), genetic algorithm-partial least squares regression (GA-PLS), and principal components-artificial neural network (PC-ANN) analysis were investigated for their application... |
|
|
Gastrointestinal dysfunction following hemolytic uremic syndrome.
Dig. Dis. Sci. 56(8) , 2241-3, (2011)
|
|
|
Stability-indicating HPLC method for simultaneous determination of clidinium bromide and chlordiazepoxide in combined dosage forms.
J. Chromatogr. Sci. 48(3) , 235-9, (2010) The study describes development and subsequent validation of a stability indicating reverse-phase high-performance liquid chromatography method for the simultaneous estimation of clidinium bromide (CLI) and chlordiazepoxide (CHLOR) from their combination drug... |
|
|
Imaging left ventricular muscarinic receptor heterogeneity: a tool to evaluate individuals at risk for sudden death?
Circ. Cardiovasc. Imaging 2(5) , 353-5, (2009)
|
|
|
Accidental acute clidinium toxicity.
Emerg. Med. J. 26(6) , 460, (2009) Clidinium bromide (N-methyl-quinuclidinyl-benzylate) is a rarely used antimuscarinic drug that is marketed in combination with chlordiazepoxide as an antispasmodic for use in irritable bowel syndrome. A case is reported of an accidental staggered overdose of ... |
|
|
Muscarinic receptor upregulation in patients with myocardial infarction: a new paradigm.
Circ. Cardiovasc. Imaging 2(5) , 365-72, (2009) Despite the major role attributed to myocardial vagal activity in left ventricular arrhythmogenesis in chronic myocardial infarction, the impact of infarction on left ventricular muscarinic receptor density remains unknown.Left ventricular muscarinic receptor... |
|
|
The determination of a degradation product in clidinium bromide drug substance by capillary electrophoresis with indirect UV detection.
J. Pharm. Biomed. Anal. 15(7) , 965-71, (1997) A capillary electrophoresis (CE) method utilizing indirect ultraviolet (UV) detection was developed for the determination of a non-UV absorbing degradation product, Ro 5-5172, in clidinium bromide drug substance. The electrophoresis buffer consisted of sodium... |
|
|
Selective binding of [3H]NMeQNB to a subpopulation of muscarinic receptors in single smooth muscle cells induces a temperature dependent decrease of receptor-[3H]NMeQNB complex.
Jpn. J. Pharmacol. 58 Suppl 2 , 358P, (1992)
|
|
|
In vivo effect of methyl-quinuclidinyl-benzylate on myocardial beta-adrenoceptor density.
Eur. J. Pharmacol. 306(1-3) , 133-8, (1996) The muscarinic receptor antagonist methyl-quinuclidinyl-benzylate decreased myocardial beta-adrenoceptor density Bmax: 20.4 +/- 2.4 pmol/ml tissue versus 33.3 +/- 4 pmol/ml tissue in control dogs (P < 0.001), as assessed by using [11C]CGP-12177 (((2S)-4-(3-t-... |