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2-甲氧基-4-硝基苯磺酰氯

2-甲氧基-4-硝基苯磺酰氯结构式
2-甲氧基-4-硝基苯磺酰氯结构式
品牌特惠专场
常用名 2-甲氧基-4-硝基苯磺酰氯 英文名 2-Methoxy-4-nitrobenzenesulfonyl chloride
CAS号 21320-91-2 分子量 251.644
密度 1.6±0.1 g/cm3 沸点 406.6±35.0 °C at 760 mmHg
分子式 C7H6ClNO5S 熔点 90-95 °C(lit.)
MSDS 中文版 美版 闪点 199.7±25.9 °C
符号 GHS05
GHS05
信号词 Danger

Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors.

Bioorg. Med. Chem. 18(15) , 5576-92, (2010)

Screening of the NCI Diversity Set-1 identified PI-083 (NSC-45382) a proteasome inhibitor selective for cancer over normal cells. Focused libraries of novel compounds based on PI-083 chloronaphthoquinone and sulfonamide moieties were synthesized to gain a bet...