1,2-亚甲二氧基苯
1,2-亚甲二氧基苯结构式
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常用名 | 1,2-亚甲二氧基苯 | 英文名 | 1,3-Benzodioxole |
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| CAS号 | 274-09-9 | 分子量 | 122.121 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 173.0±15.0 °C at 760 mmHg | |
| 分子式 | C7H6O2 | 熔点 | -18 °C | |
| MSDS | 中文版 美版 | 闪点 | 55.0±0.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Smooth photocatalytic preparation of 2-substituted 1,3-benzodioxoles.
Chemistry 17(2) , 572-9, (2011) A mild and general method for the synthesis of potentially bioactive 2-substituted-1,3-benzodioxoles is presented. This is based on the photocatalyzed activation of methylene hydrogen atoms in the presence of tetrabutylammonium decatungstate (TBADT). The meth... |
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Computer graphics analysis of the interaction of alkoxy methylenedioxybenzenes with cytochromes P4501.
Toxicol. Lett. 76(1) , 39-45, (1995) A quantitative structure-activity relationship (QSAR) in a homologous series of alkoxy methylenedioxybenzenes (MDBs) is reported. Measurements of molecular dimensions from computer-generated space-filling structures have provided values for the shape paramete... |
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Synthesis and cytotoxicity of podophyllotoxin analogues modified in the A ring.
Eur. J. Med. Chem. 38(1) , 65-74, (2003) Several podophyllotoxin derivatives lacking the methylenedioxy group or with different functionalization of the A-ring of the cyclolignan skeleton have been prepared and evaluated for their cytotoxic activities on four neoplastic cell lines (P-388, A-549, HT-... |
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Sesamol as an inhibitor of growth and lipid metabolism in Mucor circinelloides via its action on malic enzyme.
Lipids 32(6) , 605-10, (1997) Sesamol, a nonoil component of sesame seed oil, inhibited growth, fatty acid synthesis, and desaturation by Mucor circinelloides in vivo. Although sesamol also inhibited the growth of other fungi and yeasts, its effect on the lipid metabolism of M. circinello... |
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A natural component as coinitiator for unfilled dental resin composites.
J. Biomed. Mater. Res. B. Appl. Biomater. 82(1) , 44-50, (2007) A natural component, 1,3-benzodioxole (BDO), was used for the purpose of replacing the conventional amine for dental composite. Camphorquinone (CQ)/BDO was used to initiate the photopolymerization of urethane dimethacrylate (UDMA)/triethylene glycol dimethacr... |
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A spectrophotometric assay for the detection of fungal peroxygenases.
Anal. Biochem. 421(1) , 327-9, (2012) Rapid and simple spectrophotometric methods are required for the unambiguous detection of recently discovered fungal peroxygenases in vivo and in vitro. This paper describes a peroxygenase-specific assay using 5-nitro-1,3-benzodioxole as substrate. The produc... |
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DBD dyes as fluorescent probes for sensing lipophilic environments.
Bioorg. Med. Chem. Lett. 22(17) , 5367-71, (2012) Small fluorescent organic molecules based on [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD) could be used as probes for lipophillic microenvironments in aqueous solutions by indicating the critical micelles concentration of detergents and staining cell organelles... |
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Induction of rat-hepatic microsomal cytochrome P-450 and aryl hydrocarbon hydroxylase by 1,3-benzodioxole derivatives.
Xenobiotica 15(5) , 361-8, (1985) Several 1,3-benzodioxoles (BD) and related compounds were studied in relation to their ability to generate metabolite complexes with hepatic cytochrome P-450 following administration in vivo to rats. BD derivatives that formed stable metabolite complexes with... |
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Aromatic hydroxylation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) by rabbit liver microsomes.
Xenobiotica 22(4) , 395-403, (1992) 1. Metabolites formed during incubation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) with rabbit liver microsomes were examined by h.p.l.c.-electrochemical detection and g.l.c.-mass spectrometry. 2. The trifluoroacetyl derivative of... |
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Differential induction of cytochrome P450 gene expression by 4n-alkyl-methylenedioxybenzenes in primary rat hepatocyte cultures.
J. Biochem. Mol. Toxicol. 12(5) , 253-62, (1998) A well-characterized primary rat hepatocyte culture system was used to examine induction patterns of cytochrome 450 gene expression by a series of 4-n-alkyl-methylenedioxybenzene (MDBs) derivatives. Hepatocytes were treated for 24, 48, or 72 hours with 0-500 ... |