五甲基哌啶
五甲基哌啶结构式
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常用名 | 五甲基哌啶 | 英文名 | Pempidine |
|---|---|---|---|---|
| CAS号 | 79-55-0 | 分子量 | 155.28000 | |
| 密度 | 0.858 g/mL at 25 °C(lit.) | 沸点 | 187-188 °C(lit.) | |
| 分子式 | C10H21N | 熔点 | 137-141ºC | |
| MSDS | 中文版 美版 | 闪点 | 122 °F | |
| 符号 |
GHS02, GHS06 |
信号词 | Danger |
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Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes.
Neurochem. Res. 21(9) , 1141-8, (1996) The modulation of [3H]ACh release by nicotinic compounds was studied in superfused rat hippocampal synaptosomes loaded with [3H]choline, (-)-Nicotine (0.1-10 microM) evoked a dose-dependent increase in [3H]ACh release; higher concentrations were less effectiv... |
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Enhancement of naturally occurring cell death in the sympathetic and parasympathetic ganglia of the chicken embryo following blockade of ganglionic transmission.
Brain Res. 444(1) , 189-94, (1988) Both presynaptic and postsynaptic blockade of ganglionic transmission during the period of naturally occurring ganglion cell death reduced the number of surviving neurons in the sympathetic ganglia (SG) and ciliary ganglion (CG). The CG was chosen for analysi... |
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Understanding channel blocking in the nicotinic acetylcholine receptor.
Receptors Channels 7(4) , 273-88, (2001) Ion-channel blockers are molecules that obstruct the path used by ions to cross the membrane through a protein channel. Many of these are local anesthetics, toxins or drugs of abuse, and the knowledge of their mechanism of action at the atomic level is an imp... |
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Functional heterogeneity of the matrix compartment in the cat caudate nucleus as demonstrated by the cholinergic presynaptic regulation of dopamine release.
Neuroscience 50(3) , 597-610, (1992) Previously, using a new in vitro microsuperfusion procedure, we have demonstrated marked differences in the cholinergic presynaptic regulation of the release of [3H]dopamine continuously synthesized from [3H]tyrosine in two close striosomal- and matrix-enrich... |
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[Effect of pyrilene and temechin on central and pulmonary hemodynamics in the treatment of hemoptysis].
Vrach. Delo (6) , 47-9, (1988)
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Ultrastructural changes of crop-sac and lactotrophs after systemic or intraventricular administration of drugs enhancing cholinergic transmission in pigeons.
Anat. Anz. 173(4) , 199-208, (1991) The ultrastructural effects of drugs enhancing, by different mechanisms, cholinergic transmission in the crop-sac (the target for prolactin secretion in birds) and the anterior pituitary lactotrophs, were studied in pigeons (Columba livia). The systemic or in... |
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Inhibition by neosurugatoxin of nicotine-induced antinociception.
Brain Res. 375(2) , 360-2, (1986) We have found a selective inhibition of nicotine-induced antinociception in mice by neosurugatoxin (NSTX, 0.4-3.8 nmol/kg), a neurotoxin with a high affinity for ganglionic nicotinic receptors (ED50 = 0.65 nmol/kg). The toxin also reduced specific [3H]nicotin... |
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Detection of the messenger RNAs coding for the opioid peptide precursors in pituitary and adrenal by "in situ' hybridization: study in several mammal species.
Neurosci. Lett. 53(2) , 141-8, (1985) The messenger RNAs coding for opioid peptide precursors have been detected and mapped in histological sections by "in situ' hybridization using specific DNA probes labelled with 32P. Using bovine preproenkephalin A (PPA) cDNA, PPA mRNA was detected in adrenal... |
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[3H]benzylpempidine, a new radioligand for probing a putative channel site on nicotinic cholinergic receptors.
Life Sci. 60(15) , 1271-7, (1997) A study was undertaken to assess the receptor binding characteristics of [3H]4-benzylpempidine to an allosteric site on calf brain membranes associated with nicotinic cholinergic receptors and to compare the binding affinity of novel arylpempidine analogs wit... |
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Is there a functional response-overlap between 5-HT3 and nicotinic ion channel receptors?
Ann. N. Y. Acad. Sci. 861 , 255-7, (1998)
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