苏木精
苏木精结构式
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常用名 | 苏木精 | 英文名 | Hematoxylin |
|---|---|---|---|---|
| CAS号 | 517-28-2 | 分子量 | 302.279 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 579.9±50.0 °C at 760 mmHg | |
| 分子式 | C16H14O6 | 熔点 | 200 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 304.5±30.1 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis.
Cancer Res. 75(6) , 1102-12, (2015) The translation initiation factor eIF4E is an oncogene that is commonly overexpressed in primary breast cancers and metastases. In this article, we report that a pharmacologic inhibitor of eIF4E function, ribavirin, safely and potently suppresses breast tumor... |
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Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.
Hum. Gene Ther. 26(3) , 172-82, (2015) Intrauterine growth restriction (IUGR) due to placental insufficiency is a leading cause of perinatal complications for which there is no effective prenatal therapy. We have previously demonstrated that intraplacental injection of adenovirus-mediated insulin-... |
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Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.
Autophagy 10(7) , 1241-55, (2014) Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazole, a traditional antifungal drug, has been identified as a ... |
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Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.
Arch. Toxicol. 89(1) , 107-19, (2015) The use of diclofenac (DCF), a nonsteroidal anti-inflammatory drug, is associated with a high prevalence of gastrointestinal side effects. In vivo studies in rodents suggested that reactive metabolites of DCF produced by the liver or the intestine might be re... |
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Divergent effects of oxytocin treatment of obese diabetic mice on adiposity and diabetes.
Endocrinology 155(11) , 4189-201, (2014) Oxytocin has been suggested as a novel therapeutic against obesity, because it induces weight loss and improves glucose tolerance in diet-induced obese rodents. A recent clinical pilot study confirmed the oxytocin-induced weight-reducing effect in obese nondi... |
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EGFR signaling downstream of EGF regulates migration, invasion, and MMP secretion of immortalized cells derived from human ameloblastoma.
Tumour Biol. 35(11) , 11107-20, (2014) Ameloblastoma is an odontogenic tumor characterized by local invasiveness and frequent recurrence. The surrounding stroma, composed of different cell types and extracellular matrix (ECM), may influence ameloblastoma invasive behavior. Furthermore, tumor and s... |
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Detailed characterization of a long-term rodent model of critical illness and recovery.
Crit. Care Med. 43(3) , e84-96, (2015) To characterize a long-term model of recovery from critical illness, with particular emphasis on cardiorespiratory, metabolic, and muscle function.Randomized controlled animal study.University research laboratory.Male Wistar rats.Intraperitoneal injection of ... |
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Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity.
Endocrinology 156(4) , 1283-91, (2015) Neural precursor cell expressed developmentally down-regulated protein 4 (Nedd4) is the prototypical protein in the Nedd4 ubiquitin ligase (E3) family, which governs ubiquitin-dependent endocytosis and/or degradation of plasma membrane proteins. Loss of Nedd4... |
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Enhanced Retinal Ganglion Cell Survival in Glaucoma by Hypoxic Postconditioning After Disease Onset.
Neurotherapeutics 12(2) , 502-14, (2015) The neuroprotective efficacy of adaptive epigenetics, wherein beneficial gene expression changes are induced by nonharmful "conditioning" stimuli, is now well established in several acute, preclinical central nervous system injury models. Recently, in a mouse... |
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Staphylococcal enterotoxin burden determines the type of T helper cell response and pathology of the maxillary sinus mucosa in rabbits.
Int. Immunopharmacol. 23(2) , 633-41, (2015) Staphylococcal enterotoxin (SE) induces T lymphocyte activation along with nasal allergic inflammation during rhinosinusitis, but it is under debate on which types of T helper (Th) cells respond exclusively or whether they respond synergically. We hypothesize... |