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1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱

1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱结构式
1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱结构式
品牌特惠专场
常用名 1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱 英文名 1,2-dielaidoyl-sn-glycero-3-phosphocholine
CAS号 56782-46-8 分子量 786.11300
密度 N/A 沸点 N/A
分子式 C44H84NO8P 熔点 N/A
MSDS 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.

Biochim. Biophys. Acta 1848(1 Pt A) , 192-9, (2015)

The polyene antifungal antibiotic nystatin confers its biological activity by forming pores in the membranes of target cells. Exposure of only one side of the membrane to nystatin is more relevant than two-side exposure because in vivo antibiotic molecules in...

Transient pearling and vesiculation of membrane tubes under osmotic gradients.

Faraday Discuss. 161 , 167-76; discussion 273-303, (2013)

We report the experimental observation of osmotically induced transient pearling instabilities in vesicular membranes. Giant phospholipid vesicles subjected to negative osmotic gradient, which drives the influx of water in to the vesicular interior, produces ...

Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature.

Biochim. Biophys. Acta 1828(9) , 2134-42, (2013)

Arginine-rich cell-penetrating peptides, including octaarginine (R8) and HIV-1 TAT peptides, have the ability to translocate through cell membranes and transport exogenous bioactive molecules into cells. Hydrophobic counteranions such as pyrenebutyrate (PyB) ...

Molecular insight into affinities of drugs and their metabolites to lipid bilayers.

J. Phys. Chem. B 117(8) , 2403-10, (2013)

The penetration properties of drug-like molecules on human cell membranes are crucial for understanding the metabolism of xenobiotics and overall drug distribution in the human body. Here, we analyze partitioning of substrates of cytochrome P450s (caffeine, c...

Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility.

J. Colloid. Interface Sci. 405 , 312-21, (2013)

Vitamin E is an essential micronutrient for humans and animals due to its antioxidant and non-antioxidant biological activities. In this study, an emulsion titration assay was used to quantify the kinetics and extent of vitamin E and vitamin E acetate solubil...

The effect of cholesterol on the intrinsic rate of lipid flip-flop as measured by sum-frequency vibrational spectroscopy.

Faraday Discuss. 161 , 45-61; discussion 113-50, (2013)

Cholesterol is a major constituent of biological membranes in mammalian cells. Experiments have shown that cholesterol influences the physical properties of the plasma membrane, such as lateral diffusion and phase equilibrium. In addition to controlling the 2...

Switchable domain partitioning and diffusion of DNA origami rods on membranes.

Faraday Discuss. 161 , 31-43; discussion 113-50, (2013)

Recently, DNA origami became a powerful tool for custom-shaped functional biomolecules. In this paper, we present the first approach towards assembling amphipathic three-dimensional DNA origami nanostructures and assessing their dynamics on the surface of fre...

Large effect of membrane tension on the fluid-solid phase transitions of two-component phosphatidylcholine vesicles.

Proc. Natl. Acad. Sci. U. S. A. 111(1) , 179-84, (2014)

Model phospholipid membranes and vesicles have long provided insight into the nature of confined materials and membranes while also providing a platform for drug delivery. The rich thermodynamic behavior and interesting domain shapes in these membranes have p...

Computer simulations of the phase separation in model membranes.

Faraday Discuss. 161 , 63-75; discussion 113-50, (2013)

We used computer simulations to investigate the properties of model lipid membranes with coexisting phases. This is relevant for understanding lipid-lipid interactions underlying lateral organization in biological membranes. Molecular dynamics simulations wit...

Lipid phase behaviour under steady state conditions.

Faraday Discuss. 161 , 151-66; discussion 273-303, (2013)

At the interface between two regions, for example the air-liquid interface of a lipid solution, there can arise non-equilibrium situations. The water chemical potential corresponding to the ambient RH will, in general, not match the water chemical potential o...