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异丙醇

一般危化品
异丙醇结构式
异丙醇结构式
常用名 异丙醇 英文名 Isopropanol
CAS号 67-63-0 分子量 60.095
密度 0.8±0.1 g/cm3 沸点 73.0±3.0 °C at 760 mmHg
分子式 C3H8O 熔点 -89.5 °C
MSDS 中文版 美版 闪点 11.7±0.0 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Danger

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation.

Retrovirology 11 , 118, (2015)

Down-modulation of the CD4 receptor is one of the hallmarks of HIV-1 infection and it is believed to confer a selective replicative advantage to the virus in vivo. This process is mainly mediated by three viral proteins: Env, Vpu and Nef. To date, the mechani...

Comparative in vitro study on magnetic iron oxide nanoparticles for MRI tracking of adipose tissue-derived progenitor cells.

PLoS ONE 9(9) , e108055, (2014)

Magnetic resonance imaging (MRI) using measurement of the transverse relaxation time (R2*) is to be considered as a promising approach for cell tracking experiments to evaluate the fate of transplanted progenitor cells and develop successful cell therapies fo...

Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.

Mol. Pharm. 11(7) , 1991-6, (2014)

Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. Hence, high efficacy of the active ingredient without system...

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.

Cancer Chemother. Pharmacol. 75(2) , 431-7, (2015)

2-Methoxyestradiol (2ME) is a promising anti-cancer agent that disrupts the integrity and dynamics of the spindle network. In order to overcome the pharmacokinetic constraints of this compound, a panel of sulphamoylated estradiol analogues were in silico-desi...

Use of an enzyme-assisted method to improve protein extraction from olive leaves.

Food Chem. 169 , 28-33, (2014)

The improvement of protein extraction from olive leaves using an enzyme-assisted protocol has been investigated. Using a cellulase enzyme (Celluclast® 1.5L), different parameters that affect the extraction process, such as the influence and amount of organic ...

Autocrine/paracrine function of globular adiponectin: inhibition of lipid metabolism and inflammatory response in 3T3-L1 adipocytes.

J. Cell. Biochem. 116(5) , 754-66, (2015)

Adiponectin is an adipose-derived hormone, with beneficial effects on insulin sensitivity and inflammation. The aim of this study was to clarify the autocrine/paracrine effects of globular adiponectin (gAd) administrated during differentiation on the function...

Investigations on the transfer of porphyrin from o/w emulsion droplets to liposomes with two different methods.

Drug Dev. Ind. Pharm. 41(1) , 156-62, (2014)

Due to their small particle size, colloidal fat emulsions are suitable for intravenous administration. In order to obtain information on their potential in vivo performance, it is important to find a simple and effective in vitro assay to evaluate the drug re...

Studying the chemistry of cationized triacylglycerols using electrospray ionization mass spectrometry and density functional theory computations.

J. Am. Soc. Mass Spectrom. 25(8) , 1421-40, (2014)

Analysis of triacylglycerols (TAGs), found as complex mixtures in living organisms, is typically accomplished using liquid chromatography, often coupled to mass spectrometry. TAGs, weak bases not protonated using electrospray ionization, are usually ionized b...

Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification.

Biochem. J. 465(1) , 79-87, (2015)

Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal of lipid-...

Establishment of lipofection for studying miRNA function in human adipocytes.

PLoS ONE 9(5) , e98023, (2014)

miRNA dysregulation has recently been linked to human obesity and its related complications such as type 2 diabetes. In order to study miRNA function in human adipocytes, we aimed for the modulation of mature miRNA concentration in these cells. Adipocytes, ho...