地塞米松
地塞米松结构式
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常用名 | 地塞米松 | 英文名 | Dexamethasone |
|---|---|---|---|---|
| CAS号 | 50-02-2 | 分子量 | 392.461 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 568.2±50.0 °C at 760 mmHg | |
| 分子式 | C22H29FO5 | 熔点 | 255-264ºC | |
| MSDS | 中文版 美版 | 闪点 | 297.5±30.1 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Immunomodulation by the Pseudomonas syringae HopZ type III effector family in Arabidopsis.
PLoS ONE 9(12) , e116152, (2014) Pseudomonas syringae employs a type III secretion system to inject 20-30 different type III effector (T3SE) proteins into plant host cells. A major role of T3SEs is to suppress plant immune responses and promote bacterial infection. The YopJ/HopZ acetyltransf... |
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Driving cartilage formation in high-density human adipose-derived stem cell aggregate and sheet constructs without exogenous growth factor delivery.
Tissue Eng. Part A 20(23-24) , 3163-75, (2014) An attractive cell source for cartilage tissue engineering, human adipose-derived stem cells (hASCs) can be easily expanded and signaled to differentiate into chondrocytes. This study explores the influence of growth factor distribution and release kinetics o... |
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Comparative in vitro study on magnetic iron oxide nanoparticles for MRI tracking of adipose tissue-derived progenitor cells.
PLoS ONE 9(9) , e108055, (2014) Magnetic resonance imaging (MRI) using measurement of the transverse relaxation time (R2*) is to be considered as a promising approach for cell tracking experiments to evaluate the fate of transplanted progenitor cells and develop successful cell therapies fo... |
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Autocrine/paracrine function of globular adiponectin: inhibition of lipid metabolism and inflammatory response in 3T3-L1 adipocytes.
J. Cell. Biochem. 116(5) , 754-66, (2015) Adiponectin is an adipose-derived hormone, with beneficial effects on insulin sensitivity and inflammation. The aim of this study was to clarify the autocrine/paracrine effects of globular adiponectin (gAd) administrated during differentiation on the function... |
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Hesperetin inhibit adipocyte differentiation and enhance Bax- and p21-mediated adipolysis in human mesenchymal stem cell adipogenesis.
J. Biochem. Mol. Toxicol. 29(3) , 99-108, (2015) We aimed to explore the antiadipogenic and adipolysis effect of hesperetin in human mesenchymal stem cells (hMSCs)-induced adipogenesis. IC50 value of hesperetin was higher for hMSCs such as 149.2 ± 13.2 μmol for 24 h and 89.4 ± 11.4 μmol in 48 h, whereas in ... |
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Flow perfusion co-culture of human mesenchymal stem cells and endothelial cells on biodegradable polymer scaffolds.
Ann. Biomed. Eng. 42(7) , 1381-90, (2014) In this study, we investigated the effect of flow perfusion culture on the mineralization of co-cultures of human umbilical vein endothelial cells (HUVECs) and human mesenchymal stem cells (hMSCs). Osteogenically precultured hMSCs were seeded onto electrospun... |
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Effect of germinated brown rice extracts on pancreatic lipase, adipogenesis and lipolysis in 3T3-L1 adipocytes.
Lipids Health Dis. 13 , 169, (2014) This study investigated anti-obesity effects of seven different solvent (n-hexane, toluene, dicholoromethane, ethyl acetate, absolute methanol, 80% methanol and deionized water) extracts of germinated brown rice (GBR) on pancreatic lipase activity, adipogenes... |
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Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases.
BMC Mol. Biol. 16 , 6, (2015) Tendons are dense connective tissues subjected periodically to mechanical stress upon which complex responsive mechanisms are activated. These mechanisms affect not only the development of these tissues but also their healing. Despite of the acknowledged impo... |
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PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Gastroenterology 147(6) , 1405-16.e7, (2014) New drug targets are urgently needed for the treatment of patients with pancreatic ductal adenocarcinoma (PDA). Nearly all PDAs contain oncogenic mutations in the KRAS gene. Pharmacological inhibition of KRAS has been unsuccessful, leading to a focus on downs... |
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ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes.
Biochem. Pharmacol. 90(4) , 406-13, (2014) Endothelin-1 (ET-1) induces lipolysis in adipocytes, where ET-1 chronic exposure results in insulin resistance (IR) through suppression of glucose transporter (GLUT)4 translocation to the plasma membrane and consequently glucose uptake. ARF6 small GTPase, whi... |