阿坎酸钙
阿坎酸钙结构式
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常用名 | 阿坎酸钙 | 英文名 | Acamprosate calcium |
|---|---|---|---|---|
| CAS号 | 77337-73-6 | 分子量 | 200.24 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C5H10NO4S.1/2Ca | 熔点 | >300ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy.
Sci. Rep. 5 , 7608, (2015) Alzheimer disease (AD) represents a major medical problem where mono-therapeutic interventions demonstrated only a limited efficacy so far. We explored the possibility of developing a combinational therapy that might prevent the degradation of neuronal and en... |
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Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat.
Neuropsychopharmacology 39(11) , 2601-10, (2014) Since its discovery, the nociceptin/orphanin FQ (N/OFQ)-NOP receptor system has been extensively investigated as a promising target to treat alcoholism. Encouraging results obtained with the endogenous ligand N/OFQ stimulated research towards the development ... |
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Acamprosate calcium as augmentation therapy for anxiety disorders.
Ann. Pharmacother. 44 , 1930-2, (2010) Glutamate is a major excitatory neurotransmitter, while γ-aminobutyric acid (GABA) is a predominant inhibitory neurotransmitter in the central nervous system. This GABA-glutamate imbalance is thought to play a role in the development of anxiety. Acamprosate c... |
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Pharmacokinetics of acamprosate calcium in healthy Chinese subjects after oral administration of three dosage levels.
Arzneimittelforschung 59 , 631-4, (2009) To study the pharmacokinetics of acamprosate calcium (CAS 77337-73-6) in healthy Chinese subjects after oral administration of three dosage levels, 12 healthy subjects were divided into three groups and given a single oral dose of 333 or 666 or 1332 mg acampr... |
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Alcohol dependence treatments: comprehensive healthcare costs, utilization outcomes, and pharmacotherapy persistence Baser, O., et al.
Am. J. Manag. Care 8 , S222-34, (2011)
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